Cyclodipeptides (CDPs) or 2, 5-diketopiperazines (DKPs) can exert a variety of biological activities and display pronounced resistance against enzymatic hydrolysis as well as a propensity towards self-assembly into gels, relative to the linear-dipeptide counterparts. They have attracted great interest in a variety of fields spanning from functional materials to drug discovery. This concise review will analyze the latest advancements in their synthesis, self-assembly into gels, and their more innovative applications.

Diketopiperazine gels: New horizons from the self-assembly of cyclic dipeptides

Marchesan S.
2021-01-01

Abstract

Cyclodipeptides (CDPs) or 2, 5-diketopiperazines (DKPs) can exert a variety of biological activities and display pronounced resistance against enzymatic hydrolysis as well as a propensity towards self-assembly into gels, relative to the linear-dipeptide counterparts. They have attracted great interest in a variety of fields spanning from functional materials to drug discovery. This concise review will analyze the latest advancements in their synthesis, self-assembly into gels, and their more innovative applications.
2021
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11368/2991751
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