Meta-analyses have the advantage of providing a summary effect estimate when there are a number of methodologically homogenous studies that examine the same intervention in the same study populations. Fortyfive days after the publication of the Recovery trial, a meta-analysis of eight randomized trials (7,184 participants) was published, and a corresponding WHO guideline panel subsequently recommended systemic corticosteroids in patients with severe and critical COVID-19 (strong recommendation, based on moderate certainty evidence).

Caution When Comparing the Impact of Corticosteroids in COVID-19

Confalonieri, Marco
;
Salton, Francesco;Confalonieri, Paola;
2021

Abstract

Meta-analyses have the advantage of providing a summary effect estimate when there are a number of methodologically homogenous studies that examine the same intervention in the same study populations. Fortyfive days after the publication of the Recovery trial, a meta-analysis of eight randomized trials (7,184 participants) was published, and a corresponding WHO guideline panel subsequently recommended systemic corticosteroids in patients with severe and critical COVID-19 (strong recommendation, based on moderate certainty evidence).
Pubblicato
https://www.sciencedirect.com/science/article/pii/S0012369221007480?via=ihub
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339403/
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11368/2993337
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