Meta-analyses have the advantage of providing a summary effect estimate when there are a number of methodologically homogenous studies that examine the same intervention in the same study populations. Fortyfive days after the publication of the Recovery trial, a meta-analysis of eight randomized trials (7,184 participants) was published, and a corresponding WHO guideline panel subsequently recommended systemic corticosteroids in patients with severe and critical COVID-19 (strong recommendation, based on moderate certainty evidence).
Caution When Comparing the Impact of Corticosteroids in COVID-19
Confalonieri, Marco
;Salton, Francesco;Confalonieri, Paola;
2021-01-01
Abstract
Meta-analyses have the advantage of providing a summary effect estimate when there are a number of methodologically homogenous studies that examine the same intervention in the same study populations. Fortyfive days after the publication of the Recovery trial, a meta-analysis of eight randomized trials (7,184 participants) was published, and a corresponding WHO guideline panel subsequently recommended systemic corticosteroids in patients with severe and critical COVID-19 (strong recommendation, based on moderate certainty evidence).File in questo prodotto:
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Chest letter 2021.pdf
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