The authors state that sperm apoptosis is a useful indicator of male infertility in the case of varicocele, while being unable to detect Fas and Fas-L on sperm cells. At the same time, they also claim that the presence of Fas is a debated issue. We demonstrated beyond any reasonable doubt that Fas is not present in human sperm and clarified that detections of Fas from other authors were due to interference with leukocytes in seminal samples. To prove this, we performed semen analysis through a multiparameter flow cytometry method that excluded leukocytes from the sperm population.
Fas in human semen
Ricci G.
;Boscolo R.;
2022-01-01
Abstract
The authors state that sperm apoptosis is a useful indicator of male infertility in the case of varicocele, while being unable to detect Fas and Fas-L on sperm cells. At the same time, they also claim that the presence of Fas is a debated issue. We demonstrated beyond any reasonable doubt that Fas is not present in human sperm and clarified that detections of Fas from other authors were due to interference with leukocytes in seminal samples. To prove this, we performed semen analysis through a multiparameter flow cytometry method that excluded leukocytes from the sperm population.File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
Fas in human semen - J REP IMMUNOL 2022.pdf
Accesso chiuso
Tipologia:
Documento in Versione Editoriale
Licenza:
Copyright Editore
Dimensione
239.41 kB
Formato
Adobe PDF
|
239.41 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
|
Fas+in+human+semen+-+J+REP+IMMUNOL+2022-Post_print.pdf
Open Access dal 07/09/2023
Tipologia:
Bozza finale post-referaggio (post-print)
Licenza:
Creative commons
Dimensione
699.46 kB
Formato
Adobe PDF
|
699.46 kB | Adobe PDF | Visualizza/Apri |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
