Recent trends in catalysis are devoted to mimicking some peculiar features of enzymes like site selectivity, through functional group recognition, and substrate selectivity, through recognition of the entire surface of the substrate. The latter is a specific feature of enzymes that is seldomly present in homogeneous catalysis. Supramolecular catalysis, thanks to the self-assembly of simple subunits, enables the creation of cavities and surfaces whose confinement effects drive the preferential binding of a substrate among others with consequent substrate selectivity. The topic is an emerging field that exploits recognition phenomena to discriminate the reagents based on their size and shape. This review deals this cutting-edge field of research covering examples of supramolecular self-assembled molecular containers and catalysts operating in organic as well as aqueous media, with special emphasis for catalytic systems dealing with direct competitive experiments involving two or more substrates.Substrate selectivity is the property of catalysts like enzymes to pick up one substrate among many others in solution. To implement substrate selectivity in artificial homogeneous catalysts, an emerging approach in homogeneous catalysis consists in exploiting self-assembled nano-catalysts and nanocontainers. The confinement effects provide supramolecular substrate recognition before the catalytic step. This review covers recent achievements in this challenging field of research.image

Substrate Selectivity Imparted by Self‐Assembled Molecular Containers and Catalysts

Lorenzetto, Tommaso
Membro del Collaboration Group
;
Bordignon, Francesca
Membro del Collaboration Group
;
Mancin, Fabrizio
Membro del Collaboration Group
;
Scarso, Alessandro
Membro del Collaboration Group
2024-01-01

Abstract

Recent trends in catalysis are devoted to mimicking some peculiar features of enzymes like site selectivity, through functional group recognition, and substrate selectivity, through recognition of the entire surface of the substrate. The latter is a specific feature of enzymes that is seldomly present in homogeneous catalysis. Supramolecular catalysis, thanks to the self-assembly of simple subunits, enables the creation of cavities and surfaces whose confinement effects drive the preferential binding of a substrate among others with consequent substrate selectivity. The topic is an emerging field that exploits recognition phenomena to discriminate the reagents based on their size and shape. This review deals this cutting-edge field of research covering examples of supramolecular self-assembled molecular containers and catalysts operating in organic as well as aqueous media, with special emphasis for catalytic systems dealing with direct competitive experiments involving two or more substrates.Substrate selectivity is the property of catalysts like enzymes to pick up one substrate among many others in solution. To implement substrate selectivity in artificial homogeneous catalysts, an emerging approach in homogeneous catalysis consists in exploiting self-assembled nano-catalysts and nanocontainers. The confinement effects provide supramolecular substrate recognition before the catalytic step. This review covers recent achievements in this challenging field of research.image
2024
Pubblicato
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.202301811
File in questo prodotto:
File Dimensione Formato  
Chemistry A European J - 2023 - Lorenzetto - Substrate Selectivity Imparted by Self‐Assembled Molecular Containers and.pdf

accesso aperto

Tipologia: Documento in Versione Editoriale
Licenza: Creative commons
Dimensione 10.68 MB
Formato Adobe PDF
10.68 MB Adobe PDF Visualizza/Apri
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11368/3068858
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 0
  • ???jsp.display-item.citation.isi??? 0
social impact