We conducted a screening analysis to assess the presence of a characteristic extracellular circulating microRNAs (ci- miRNAs) profile in Behçet’s syndrome (BS). Total RNA was extracted from platelets-free plasma (PFP) samples obtained from 16 BS patients and 18 healthy con- trols. Ci-miRNAs profiling was conducted by using dedicated Agilent microarray hybridization and data extraction tech- nology. Statistical analysis of data extracted from microarray scanning revealed the deregulation of 36 ci-miRNAs, which turned out be differentially expressed between BS patients and healthy controls. Detailed experimental methods and data analysis were described here. The raw and normalized microarray data were deposited into Gene Expression Omnibus (GEO) under accession num- ber GSE145191.
Circulating miRNome profiling data in Behçet's syndrome
Emmi, Giacomo;Arcangeli, Annarosa
2021-01-01
Abstract
We conducted a screening analysis to assess the presence of a characteristic extracellular circulating microRNAs (ci- miRNAs) profile in Behçet’s syndrome (BS). Total RNA was extracted from platelets-free plasma (PFP) samples obtained from 16 BS patients and 18 healthy con- trols. Ci-miRNAs profiling was conducted by using dedicated Agilent microarray hybridization and data extraction tech- nology. Statistical analysis of data extracted from microarray scanning revealed the deregulation of 36 ci-miRNAs, which turned out be differentially expressed between BS patients and healthy controls. Detailed experimental methods and data analysis were described here. The raw and normalized microarray data were deposited into Gene Expression Omnibus (GEO) under accession num- ber GSE145191.Pubblicazioni consigliate
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