This study presents a five-year follow-up of 436 patients who experienced mild COVID-19 in early 2020, focusing on long-term smell and taste dysfunction. At the onset, 66.7% reported altered chemosensory perception. Although most recovered over time, 7.6% still reported dysfunction after five years. Recovery rates steadily improved, reaching 91.1% among those initially affected. Despite the improvements, persistent symptoms remain a concern for a subset of patients, highlighting ongoing quality-of-life and safety issues. The study underscores the need for long-term monitoring and potential rehabilitation strategies for chemosensory dysfunction. Limitations include self-reported data, no objective testing, and focus on pre-Omicron infections.

Five-Year Longitudinal Assessment of Self-reported COVID-19-Related Chemosensory Dysfunction

Boscolo-Rizzo, Paolo;Spinato, Giacomo;De Colle, Rebecca;Vaira, Luigi Angelo;Tirelli, Giancarlo
2025-01-01

Abstract

This study presents a five-year follow-up of 436 patients who experienced mild COVID-19 in early 2020, focusing on long-term smell and taste dysfunction. At the onset, 66.7% reported altered chemosensory perception. Although most recovered over time, 7.6% still reported dysfunction after five years. Recovery rates steadily improved, reaching 91.1% among those initially affected. Despite the improvements, persistent symptoms remain a concern for a subset of patients, highlighting ongoing quality-of-life and safety issues. The study underscores the need for long-term monitoring and potential rehabilitation strategies for chemosensory dysfunction. Limitations include self-reported data, no objective testing, and focus on pre-Omicron infections.
2025
23-ago-2025
Epub ahead of print
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11368/3113479
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