Giant cell arteritis is a systemic vasculitis that causes inflammation in medium- and large-sized blood vessels.The condition can lead to irreversible blindness if not recognised and treated promptly with high-dose steroids. Clinical manifestations typically include headache, jaw pain, fever, and fatigue. However, unusual manifestations of the disease have been reported, including pulmonary nodules, uveitis, pericarditis, and stroke. We report a case of biopsy-confirmed giant cell arteritis in a patient found to have renal cell carcinoma, exhibiting these unusual manifestations simultaneously. This case report demonstrates the atypical presentation that giant cell arteritis may have and the importance of having a high clinical suspicion for the condition.

Unusual systemic conditions in a patient with giant cell arteritis / El-Jack, Khalid; Naeem, Fawaz; Safadi, Jenelle; Marangoni, Dario; Solomon, Alexander M; Fogt, Franz; Liu, Grant T; Tamhankar, Madhura A. - In: MODERN RHEUMATOLOGY CASE REPORTS. - ISSN 2472-5625. - 9:2(2025), pp. rxaf014."-"-rxaf014."-". [10.1093/mrcr/rxaf014]

Unusual systemic conditions in a patient with giant cell arteritis

Marangoni, Dario;
2025-01-01

Abstract

Giant cell arteritis is a systemic vasculitis that causes inflammation in medium- and large-sized blood vessels.The condition can lead to irreversible blindness if not recognised and treated promptly with high-dose steroids. Clinical manifestations typically include headache, jaw pain, fever, and fatigue. However, unusual manifestations of the disease have been reported, including pulmonary nodules, uveitis, pericarditis, and stroke. We report a case of biopsy-confirmed giant cell arteritis in a patient found to have renal cell carcinoma, exhibiting these unusual manifestations simultaneously. This case report demonstrates the atypical presentation that giant cell arteritis may have and the importance of having a high clinical suspicion for the condition.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11368/3121499
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