Pseudoangiomatous stromal hyperplasia (PASH) is a rare benign breast lesion in children. We report a 10-year-old girl with hormonally driven gigantomastia and recurrent mastitis, interpreted as a secondary inflammatory complication of rapid breast enlargement. Treatment with oral tamoxifen led to arrest of breast growth and resolution of inflammatory symptoms. This case supports tamoxifen as a potential non-surgical option for hormonally driven pediatric gigantomastia associated with PASH.
Tamoxifen therapy in juvenile gigantomastia associated with PASH: a case report / Coslovich, Simone; Bortul, Marina; Zanconati, Fabrizio; Tornese, Gianluca. - In: FRONTIERS IN PEDIATRICS. - ISSN 2296-2360. - ELETTRONICO. - 14:(2026), pp. 1765982."-"-1765982."-". [10.3389/fped.2026.1765982]
Tamoxifen therapy in juvenile gigantomastia associated with PASH: a case report
Coslovich, Simone
Primo
;Bortul, MarinaSecondo
;Zanconati, FabrizioPenultimo
;Tornese, GianlucaUltimo
2026-01-01
Abstract
Pseudoangiomatous stromal hyperplasia (PASH) is a rare benign breast lesion in children. We report a 10-year-old girl with hormonally driven gigantomastia and recurrent mastitis, interpreted as a secondary inflammatory complication of rapid breast enlargement. Treatment with oral tamoxifen led to arrest of breast growth and resolution of inflammatory symptoms. This case supports tamoxifen as a potential non-surgical option for hormonally driven pediatric gigantomastia associated with PASH.| File | Dimensione | Formato | |
|---|---|---|---|
|
Articolo 2026 Tamoxifen therapy in juvenile gigantomastia associated with PASH- a case report.pdf
accesso aperto
Tipologia:
Documento in Versione Editoriale
Licenza:
Creative commons
Dimensione
749.75 kB
Formato
Adobe PDF
|
749.75 kB | Adobe PDF | Visualizza/Apri |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
