Lymphomatoid papulosis associated with Hodgkin lymphoma: two case reports and a short review of literature

Lymphomatoid papulosis (LyP) is a rare lymphoproliferative disorder, characterized by the development of self-regressing crops of papular, papulo-necrotic and/or nodular erythematous skin lesions with histologic features of a cutaneous CD30+ T-cell lymphoma. LyP shows an estimated world-wide incidence of 1.2 – 1.9 cases per million and has an excellent prognosis, with a 5-year diseasespecific survival rate close to 100%. However, in 20% – 50% of cases, LyP may be associated with another type of cutaneous or systemic lymphoma, most commonly mycosis fungoides (MF), primary cutaneous anaplastic large-cell lymphoma (pcALCL), and more rarely Hodgkin lymphoma (HL).1,2 In this paper, we report two cases of HL-associated LyP along with a brief literature review.