DURIGUTTO, PAOLO
DURIGUTTO, PAOLO
Dipartimento di Scienze della Vita
Personale esterno ed autonomi
A Human Monoclonal Antibody Against Domain I Of beta 2-Glycoprotein I prevents Clotting and Fetal Loss Induced By Polyclonal Anti-Phospholipid Antibodies In Animal Models.
2013-01-01 Agostinis, C; Durigutto, Paolo; Sblattero, Daniele; Borghi, Mo; Grossi, C; Bulla, Roberta; Macor, Paolo; Meroni, Pl; Tedesco, F.
A non-complement-fixing antibody to 2 glycoprotein I as a novel therapy for antiphospholipid syndrome
2014-01-01 Agostinis, C.; Durigutto, Paolo; Sblattero, Daniele; Borghi, M. O.; Grossi, C.; Guida, F.; Bulla, Roberta; Macor, Paolo; Pregnolato, F.; Meroni, P. L.; Tedesco, Francesco
A novel complement-fixing IgM antibody targeting GPC1 as a useful immunotherapeutic strategy for the treatment of pancreatic ductal adenocarcinoma
2023-01-01 Busato, Davide; Capolla, Sara; Durigutto, Paolo; Mossenta, Monica; Bozzer, Sara; Sblattero, Daniele; Macor, Paolo; Dal Bo, Michele; Toffoli, Giuseppe
Bispecific antibodies targeting tumor-associated antigens and neutralizing complement regulators increase the efficacy of antibody-based immunotherapy in mice.
2015-01-01 Macor, Paolo; Secco, E; Mezzaroba, Nelly; Zorzet, Sonia; Durigutto, Paolo; Gaiotto, T; De Maso, L; Biffi, S; Garrovo, C; Capolla, Sara; Tripodo, C; Gattei, V; Marzari, Roberto; Tedesco, Francesco; Sblattero, Daniele
C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation
2016-01-01 Bulla, Roberta; Tripodo, Claudio; Rami, Damiano; Ling, Guang Sheng; Agostinis, Chiara; Guarnotta, Carla; Zorzet, Sonia; Durigutto, Paolo; Botto, Marina; Tedesco, Francesco
Complement Activation and Thrombin Generation by MBL Bound to β2-Glycoprotein I
2020-01-01 Durigutto, P.; Macor, P.; Pozzi, N.; Agostinis, C.; Bossi, F.; Meroni, P. L.; Grossi, C.; Borghi, M. O.; Planer, W.; Garred, P.; Tedesco, F.
Complement activation in antiphospholipid syndrome and its inhibition to prevent rethrombosis after arterial surgery
2016-01-01 Meroni, Pier Luigi; Macor, Paolo; Durigutto, Paolo; De Maso, Luca; Gerosa, Maria; Ferraresso, Mariano; Borghi, Maria Orietta; Mollnes, Tom Eirik; Tedesco, Francesco
Complement C1q and C8beta deficiency in an individual with recurrent bacterial meningitis and adult-onset systemic lupus erythematosus-like illness.
2008-01-01 Pickering, M. C.; Macor, Paolo; Fish, J.; Durigutto, Paolo; Bossi, Fleur; Petry, F.; Botto, M.; Tedesco, Francesco
Critical role and therapeutic control of the lectin pathway of complement activation in an abortion-prone mouse mating
2015-01-01 Petitbarat, Marie; Durigutto, Paolo; Macor, Paolo; Bulla, Roberta; Palmioli, Alessandro; Bernardi, Anna; De Simoni, Maria Grazia; Ledee, Nathalie; Chaouat, Gerard; Tedesco, Francesco
FRI0030 Anti-TNF-α Antibody Targeted To Inflamed Synovial Tissue for The Treatment of Rheumatoid Arthritis
2016-01-01 Colombo, Federico; Sblattero, Daniele; DE MASO, Luca; Durigutto, Paolo; Biffi, Stefania; Belmonte, B.; Tripodo, MARIA CHIARA; Meroni, P. L.; Tedesco, Francesco; Macor, Paolo
Multiple-Organ Complement Deposition on Vascular Endothelium in COVID-19 Patients
2021-01-01 Macor, Paolo; Durigutto, Paolo; Mangogna, Alessandro; Bussani, Rossana; De Maso, Luca; D’Errico, Stefano; Zanon, Martina; Pozzi, Nicola; Meroni, Pier Luigi; Tedesco, Francesco
New insight into antiphospholipid syndrome: antibodies to β2glycoprotein I-domain 5 fail to induce thrombi in rats
2019-01-01 Durigutto, Paolo; Grossi, Claudia; Borghi, Maria Orietta; Macor, Paolo; Pregnolato, Francesca; Raschi, Elena; Myers, Michael P; de Groot, Philip G; Meroni, Pier Luigi; Tedesco, Francesco
OP0023 Targeted Polymeric Nanoparticles as Diagnostic and Therapeutic Tool for Rheumatoid Arthritis
2016-01-01 Colombo, Federico; Nunez, L.; Durigutto, Paolo; Biffi, Stefania; Rampazzo, E.; Belmonte, B.; Sblattero, Daniele; Gulino, A.; Meroni, P. L.; Tedesco, Francesco; Macor, Paolo
Osteoprotegerin increases leukocyte adhesion to endothelial cells both in vitro and in vivo.
2007-01-01 Zauli, Giorgio; Corallini, Federica; Bossi, Fleur; Fischetti, Fabio; Durigutto, Paolo; Celeghini, Claudio; Tedesco, Francesco; Secchiero, P.
Plasminogen activator-coated nanobubbles targeting cell-bound β2-glycoprotein I as a novel thrombus-specific thrombolytic strategy
2023-01-01 Macor, Paolo; Durigutto, Paolo; Argenziano, Monica; Smith-Jackson, Kate; Capolla, Sara; Di Leonardo, Valeria; Marchbank, Kevin; Tolva, Valerio Stefano; Semeraro, Fabrizio; Ammollo, Concetta T; Colucci, Mario; Cavalli, Roberta; Meroni, Pierluigi; Tedesco, Francesco
Prevention of arthritis by locally synthesized recombinant antibody neutralizing complement component C5
2013-01-01 Durigutto, Paolo; Macor, Paolo; Ziller, Federica; De Maso, L; Fischetti, Fabio; Marzari, Roberto; Sblattero, Daniele; Tedesco, Francesco
Selective therapeutic control of C5a and the terminal complement complex by anti-C5 single-chain Fv in an experimental model of antigen-induced arthritis in rats.
2007-01-01 Fischetti, Fabio; Durigutto, Paolo; Macor, Paolo; Marzari, Roberto; Carretta, Renzo; Tedesco, Francesco
Targeted delivery of neutralizing anti-C5 antibody to renal endothelium prevents complement- dependent tissue damage
2017-01-01 Durigutto, Paolo; Sblattero, Daniele; Biffi, Stefania; DE MASO, Luca; Garrovo, Chiara; Baj, Gabriele; Colombo, Federico; Fischetti, Fabio; Di Naro, Antonio F.; Tedesco, Francesco; Macor, Paolo
Targeted nanoparticles and complement activation
2017-01-01 Macor, Paolo; Capolla, Sara; Colombo, Federico; DE MASO, Luca; Durigutto, Paolo; Tedesco, Francesco; Macor, Paolo
Targeting CD34+ cells of the inflamed synovial endothelium by guided nanoparticles for the treatment of rheumatoid arthritis
2019-01-01 Colombo, F.; Durigutto, P.; De Maso, L.; Biffi, S.; Belmonte, B.; Tripodo, C.; Oliva, R.; Bardini, P.; Marini, G. M.; Terreno, E.; Pozzato, G.; Rampazzo, E.; Bertrand, J.; Feuerstein, B.; Javurek, J.; Havrankova, J.; Pitzalis, C.; Nunez, L.; Meroni, P.; Tedesco, F.; Sblattero, D.; Macor, P.