The potential role of PTI-1, in the natural story of prostate adenocarcinoma remains to be fullydetermined. PTI-1 expression was evaluated in human prostate cancer cell lines and in paraffinembeddedarchive tissues. PTI-1 expression was found in Mycoplasma infected but not in noninfectedcells. The lack of PTI-1 expression was also confirmed in fixed and paraffin-embeddedhuman cancer prostate biopsies. The overall data indicate that, in prostate tumor cell lines, PTI-1 presence parallels Mycoplasma infection suggesting that PTI-1 might not necessarily play amajor role in the onset of prostate tumorigenesis.
Prostate Tumour-Inducing gene-1 analysis in human prostate cancer cells and tissue in relation to Mycoplasma infection / Scaggiante, B., Bonin, S., Cristiano, L., Siracusano, S., Stanta, G., Dapas, B., Giansante, C., Fiotti, N., Grassi, G.. - In: CANCER INVESTIGATION. - ISSN 0735-7907. - STAMPA. - 26(8):(2008), pp. 800-808. [10.1080/07357900701874633]
Prostate Tumour-Inducing gene-1 analysis in human prostate cancer cells and tissue in relation to Mycoplasma infection
SCAGGIANTE, BRUNA;BONIN, Serena;SIRACUSANO, SALVATORE;STANTA, GIORGIO;DAPAS, BARBARA;GIANSANTE, CARLO;FIOTTI, NICOLA;GRASSI, GABRIELE
2008-01-01
Abstract
The potential role of PTI-1, in the natural story of prostate adenocarcinoma remains to be fullydetermined. PTI-1 expression was evaluated in human prostate cancer cell lines and in paraffinembeddedarchive tissues. PTI-1 expression was found in Mycoplasma infected but not in noninfectedcells. The lack of PTI-1 expression was also confirmed in fixed and paraffin-embeddedhuman cancer prostate biopsies. The overall data indicate that, in prostate tumor cell lines, PTI-1 presence parallels Mycoplasma infection suggesting that PTI-1 might not necessarily play amajor role in the onset of prostate tumorigenesis.Pubblicazioni consigliate
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