Systemic inflammation contributes to obesity-associated complications. The short pentraxin C-reactive protein (CRP) is a validated inflammatory marker, whereas long pentraxin-3 (PTX3) limits inflammation and is adaptively stimulated by proinflammatory cytokines in vitro. Severely obese (SO) patients (body mass index [BMI]>40] have the highest obesity-associated complications and increasingly undergo surgical treatment. SO-associated changes in plasma PTX3 and their interactions with systemic inflammation are, however, unknown.

Gastric bypass-induced weight loss alters obesity-associated patterns of plasma pentraxin-3 and systemic inflammatory markers

BARAZZONI, ROCCO;PALMISANO, SILVIA;GORTAN CAPPELLARI, GIANLUCA;GIURICIN, MICHELA;MORETTI, ELISA;VINCI, PIERANDREA;SEMOLIC, ANNA MARIA;GUARNIERI, GIANFRANCO;ZANETTI, MICHELA;de Manzini, Nicolo'
2016

Abstract

Systemic inflammation contributes to obesity-associated complications. The short pentraxin C-reactive protein (CRP) is a validated inflammatory marker, whereas long pentraxin-3 (PTX3) limits inflammation and is adaptively stimulated by proinflammatory cytokines in vitro. Severely obese (SO) patients (body mass index [BMI]>40] have the highest obesity-associated complications and increasingly undergo surgical treatment. SO-associated changes in plasma PTX3 and their interactions with systemic inflammation are, however, unknown.
http://www.sciencedirect.com/science/article/pii/S155072891500115X
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11368/2844694
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