Human Beta Defensin-1 (hBD-1) is a component of the innate immune system, the first line of defence against pathogens, already reported as involved in the susceptibility to HIV-1 infection and HIV-1 mother-to-child transmission (MTCT) in different populations. We investigated the role of DEFB1 gene (encoding for hBD-1) functional polymorphisms in the susceptibility to HIV-1 MTCT in a population from Zambia.

DEFB1 polymorphisms and HIV-1 mother-to-child transmission in Zambian population

Zupin, Luisa
;
Polesello, Vania;Segat, Ludovica;Crovella, Sergio
2018-01-01

Abstract

Human Beta Defensin-1 (hBD-1) is a component of the innate immune system, the first line of defence against pathogens, already reported as involved in the susceptibility to HIV-1 infection and HIV-1 mother-to-child transmission (MTCT) in different populations. We investigated the role of DEFB1 gene (encoding for hBD-1) functional polymorphisms in the susceptibility to HIV-1 MTCT in a population from Zambia.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11368/2921049
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