The DYRK1A gene encodes for a dual-specific tyrosine phosphorylation-regulated kinase 1A involved in different cellular processes such as cell differentiation, proliferation and survival. This tyrosine kinase plays a key role in brain growth and function. Indeed, haploinsufficiency of DYRK1A results in defective kinase activity and is responsible for mental retardation autosomal dominant 7 (MRD7).
Tregs and Th17 lymphocytes in human DYRK1A haploinsufficiency
Valencic E.;Piscianz E.;Tommasini A.;Faletra F.;Todaro F.;
2019-01-01
Abstract
The DYRK1A gene encodes for a dual-specific tyrosine phosphorylation-regulated kinase 1A involved in different cellular processes such as cell differentiation, proliferation and survival. This tyrosine kinase plays a key role in brain growth and function. Indeed, haploinsufficiency of DYRK1A results in defective kinase activity and is responsible for mental retardation autosomal dominant 7 (MRD7).File in questo prodotto:
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