Objectives: A multicentre European randomized control trial - European Uncomplicated Type B Aortic Repair (EU-TBAR) is being developed to compare pre-emptive TEVAR with custom-made devices vs conventional OMT. The pre-trial set-up is confluent on different pillars, including evaluation of 1) European activity, trends, and governance, 2) outcome reporting, and 3) cost evaluation. This article aimed to demonstrate the observational cross-sectional survey results from participating centres and highlight the risk assessment, activity, practices, and governance of uncomplicated type B aortic dissection (uTBAD). Methods: This observational cross-sectional European survey used a questionnaire that examined the understanding, risk assessment, local governance oversight, and clinical activity of uTBAD. The data were collected and managed using Research Electronic Data Capture (REDCap). Results: Out of 43 surveyed surgeons, 37 (86%) responded within a month from 14 European countries. Most reported low annual uTBAD encounters, with autumn being the most common season for cases. Pre-emptive TEVAR was recommended by 43.2% of participants, who favoured subacute intervention timing. The Gore TAG was the most used TEVAR device, and custom devices were available for 73% of respondents. Risk factors for uTBAD were ranked, with 'Rapid Aortic Enlargement' deemed most critical. A majority of centres had protocols and multidisciplinary teams, with most having readily available radiology services. Only 45.9% had transfer services to specialised centres. Conclusion: UTBAD remains a misnomer of a dynamic, ongoing disease process requiring early diagnosis and intervention. Pre-emptive TEVAR in high-risk uTBAD is becoming more common, with encouraging results prompting an expansion of indication criteria to a broader uTBAD population managed conservatively. Nevertheless, further evidence is needed through large RCTs, mainly European collaboratives, to reach a definitive conclusion on the optimum surgical management of uTBAD.
Uncomplicated Type B Aortic Dissection: A European Multicentre Cross-Sectional Evaluation / Bashir, Mohamad; Jubouri, Matti; Surkhi, Abdelaziz O.; Williams, Ian M.; Davidovic, Lazar B.; Koncar, Igor; Baltrūnas, Tomas; Kunt, Aysegul; Tanyeli, Ömer; Bayram, Muhammed; Ugur, Murat; Rossi, Giovanni; Stelzmueller, Marie-Elisabeth; Hoksbergen, Arjan W. J.; Jongkind, Vincent; Bertoglio, Luca; Zacà, Sergio; Mansour, Wassim; Sirignano, Pasqualino; D'Oria, Mario; Tolva, Valerio Stefano; Van Herzeele, Isabelle; Klincheva, Milka; Atanasov, Zvonka; Bartoli, Stefano; Bellosta, Raffaello; Chisci, Emiliano; Guagliano, Alberto; Teraa, Martin; Ivak, Peter; Recicarova, Sandra; Pellenc, Quentin; Heijmen, Robin; Pfister, Karin; Piffaretti, Gabriele; Hutchings, Hayley; Holland, Gail; Bailey, Damian M.; Thielmann, Matthias; Jakob, Heinz. - In: ANNALS OF VASCULAR SURGERY. - ISSN 0890-5096. - 114:(2025), pp. 340-349. [10.1016/j.avsg.2024.09.067]
Uncomplicated Type B Aortic Dissection: A European Multicentre Cross-Sectional Evaluation
D'Oria, Mario;
2025-01-01
Abstract
Objectives: A multicentre European randomized control trial - European Uncomplicated Type B Aortic Repair (EU-TBAR) is being developed to compare pre-emptive TEVAR with custom-made devices vs conventional OMT. The pre-trial set-up is confluent on different pillars, including evaluation of 1) European activity, trends, and governance, 2) outcome reporting, and 3) cost evaluation. This article aimed to demonstrate the observational cross-sectional survey results from participating centres and highlight the risk assessment, activity, practices, and governance of uncomplicated type B aortic dissection (uTBAD). Methods: This observational cross-sectional European survey used a questionnaire that examined the understanding, risk assessment, local governance oversight, and clinical activity of uTBAD. The data were collected and managed using Research Electronic Data Capture (REDCap). Results: Out of 43 surveyed surgeons, 37 (86%) responded within a month from 14 European countries. Most reported low annual uTBAD encounters, with autumn being the most common season for cases. Pre-emptive TEVAR was recommended by 43.2% of participants, who favoured subacute intervention timing. The Gore TAG was the most used TEVAR device, and custom devices were available for 73% of respondents. Risk factors for uTBAD were ranked, with 'Rapid Aortic Enlargement' deemed most critical. A majority of centres had protocols and multidisciplinary teams, with most having readily available radiology services. Only 45.9% had transfer services to specialised centres. Conclusion: UTBAD remains a misnomer of a dynamic, ongoing disease process requiring early diagnosis and intervention. Pre-emptive TEVAR in high-risk uTBAD is becoming more common, with encouraging results prompting an expansion of indication criteria to a broader uTBAD population managed conservatively. Nevertheless, further evidence is needed through large RCTs, mainly European collaboratives, to reach a definitive conclusion on the optimum surgical management of uTBAD.| File | Dimensione | Formato | |
|---|---|---|---|
|
Uncomplicated Type B Aortic Dissection - A European Multicentre Cross-Sectional Evaluation.pdf
Accesso chiuso
Tipologia:
Documento in Versione Editoriale
Licenza:
Copyright Editore
Dimensione
4.96 MB
Formato
Adobe PDF
|
4.96 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.


