Atopic dermatitis (AD) is a common inflammatory skin disease resulting from the interplay between environmental, immunological and genetic factors. In our study, we investigated the role of three single nucleotide polymorphisms (SNPs) at 5'-UTR of DEFB1 gene, encoding for the human beta defensin-1, on the susceptibility to develop AD in a group of Brazilian children and adolescents.
Beta defensin-1 gene (DEFB1) polymorphisms are not associated with atopic dermatitis in children and adolescents from northeast Brazil (Recife, Pernambuco) / Segat, Ludovica; Guimarães, Rafael L; Brandão, Lucas A. C; Rocha, Cintia R. C; Zanin, Valentina; Trevisiol, Chiara; de Lima Filho, José Luiz; Crovella, Sergio. - In: INTERNATIONAL JOURNAL OF DERMATOLOGY. - ISSN 0011-9059. - 49:6(2010), pp. 653-657. [10.1111/j.1365-4632.2009.04343.x]
Beta defensin-1 gene (DEFB1) polymorphisms are not associated with atopic dermatitis in children and adolescents from northeast Brazil (Recife, Pernambuco)
SEGAT, LUDOVICA;ZANIN, VALENTINA;TREVISIOL, CHIARA;CROVELLA, SERGIO
2010-01-01
Abstract
Atopic dermatitis (AD) is a common inflammatory skin disease resulting from the interplay between environmental, immunological and genetic factors. In our study, we investigated the role of three single nucleotide polymorphisms (SNPs) at 5'-UTR of DEFB1 gene, encoding for the human beta defensin-1, on the susceptibility to develop AD in a group of Brazilian children and adolescents.Pubblicazioni consigliate
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