FEDERICO, STEPHANIE
FEDERICO, STEPHANIE
Dipartimento di Scienze Chimiche e Farmaceutiche
Settore CHIM/08 - Chimica Farmaceutica
Docenti di ruolo di IIa fascia
"Dual Anta-Inhibitors" of the A(2A) Adenosine Receptor and Casein Kinase CK1delta: Synthesis, Biological Evaluation, and Molecular Modeling Studies
2023-01-01 Spinaci, A; Buccioni, M; Catarzi, D; Cui, C; Colotta, V; Dal Ben, D; Cescon, E; Francucci, B; Grieco, I; Lambertucci, C; Marucci, G; Bassani, D; Pavan, M; Varano, F; Federico, S; Spalluto, G; Moro, S; Volpini, R
1,2,4-Triazolo[1,5-a]-1,3,5-triazine nucleus: a possible template for adenosine receptor subtypes.
2011-01-01 Federico, Stephanie; Paoletta, Silvia; Cheong, Siew Lee; Pastorin, Giorgia; Cacciari, Barbara; Stragliotto, Stefano; Klotz, Karl Norbert; Siegel, Jeffrey; Gao, Zhan Guo; Jacobson, Kenneth A.; Moro, Stefano; Spalluto, Giampiero
1,2,4]Triazolo[1,5-c]pyrimidines as New Potent Human A3 Adenosine Receptor Antagonists.
2013-01-01 Spalluto, Giampiero; Federico, Stephanie; Ciancetta, Antonella; Cacciari, Barbara; Klotz, Karl Norbert; Moro, Stefano
5,7-Disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazines as pharmacological tools to explore the antagonist selectivity profiles toward adenosine receptors
2016-01-01 Federico, Stephanie; Ciancetta, Antonella; Porta, Nicola; Redenti, Sara; Pastorin, Giorgia; Cacciari, Barbara; Klotz, Karl Norbert; Moro, Stefano; Spalluto, Giampiero
5-Alkylamino-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines. Influence of the Substituent on the Affinity at the Adenosine Receptor Subtypes
2011-01-01 Federico, Stephanie; Paoletta, Silvia; Cheong, Siew Lee; Cacciari, Barbara; Klotz, Karl Norbert; Pastorin, Giorgia; Moro, Stefano; Spalluto, Giampiero
8-(2-Furyl)adenine derivatives as A2A adenosine receptor ligands
2013-01-01 Diego Dal, Ben; Michela, Buccioni; Catia, Lambertucci; Ajiroghene, Thomas; Karl Norbert, Klotz; Federico, Stephanie; Barbara, Cacciari; Spalluto, Giampiero; Rosaria, Volpini
[1,2,4]Triazolo[1,5-a][1,3,5]Triazine Derivatives as Antagonists for the Adenosine Receptors: a Preliminary Study on Affinity at the A3 Subtype
2013-01-01 Federico, Stephanie; Ciancetta, Antonella; Cacciari, Barbara; Klotz, Karl Norbert; Moro, Stefano; Spalluto, Giampiero
[1,2,4]Triazolo[1,5-c]pyrimidine Nucleus as Adenosine Receptor Antagonists: Shift in Selectivity from A2A to A3 Adenosine Receptors.
2012-01-01 Federico, Stephanie; Ciancetta, Antonella; Paoletta, Silvia; Cacciari, Barbara; Klotz, Karl Norbert; Moro, Stefano; Spalluto, Giampiero
[1,2,4]triazolo[1,5-c]pyrimidines as A(3) adenosine receptor antagonists
2014-01-01 Federico, Stephanie; Redenti, Sara; Ciancetta, Antonella; Cacciari, Barbara; Klotz, Karl Norbert; Moro, Stefano; Spalluto, Giampiero
[1,2,4]Triazolo[1,5-c]pyrimidines as adenosine receptor antagonists: Modifications at the 8 position to reach selectivity towards A3 adenosine receptor subtype
2018-01-01 Federico, Stephanie; Margiotta, Enrico; Salmaso, Veronica; Pastorin, Giorgia; Kachler, Sonja; Klotz, Karl-Norbert; Moro, Stefano; Spalluto, Giampiero
[1,2,4]Triazolo[1,5-c]pyrimidines as Tools to Investigate A3 Adenosine Receptors in Cancer Cell Lines
2023-01-01 Federico, S.; Persico, M.; Trevisan, L.; Biasinutto, C.; Bolcato, G.; Salmaso, V.; Da Ros, T.; Gianferrara, T.; Prencipe, F.; Kachler, S.; Klotz, K. -N.; Pacor, S.; Moro, S.; Spalluto, G.
A Computational Workflow for the Identification of Novel Fragments Acting as Inhibitors of the Activity of Protein Kinase CK1δ
2021-01-01 Bolcato, Giovanni; Cescon, Eleonora; Pavan, Matteo; Bissaro, Maicol; Bassani, Davide; Federico, Stephanie; Spalluto, Giampiero; Sturlese, Mattia; Moro, Stefano
A facile and novel synthesis of N2-, C6-substituted pyrazolo[3,4- d ]pyrimidine-4 carboxylate derivatives as adenosine receptor antagonists
2015-01-01 Venkatesan, G; Paira, P.; Cheong, S. L.; Federico, Stephanie; Klotz, K. N.; Spalluto, Giampiero; Pastorin, G.
A novel conjugated agent between dopamine and an A2A adenosine receptor antagonists as a potential anti-Parkinson multitarget approach.
2012-01-01 Alessandro Dal, Piaz; Barbara, Cacciari; Chiara Beatrice, Vicentini; Fabrizio, Bortolotti; Spalluto, Giampiero; Federico, Stephanie; Barbara, Pavan; Fabrizio, Vincenzi; Pier Andrea, Borea; Katia, Varani
A Triazolotriazine-Based Dual GSK-3β/CK-1δ Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition
2019-01-01 Redenti, Sara; Marcovich, Irene; De Vita, Teresa; Pérez, Concepción; De Zorzi, Rita; Demitri, Nicola; Perez, Daniel I.; Bottegoni, Giovanni; Bisignano, Paola; Bissaro, Maicol; Moro, Stefano; Martinez, Ana; Storici, Paola; Spalluto, Giampiero; Cavalli, Andrea; Federico, Stephanie
A2Aadenosine receptor antagonists as therapeutic candidates: Are they still an interesting challenge?
2018-01-01 Cacciari, Barbara; Spalluto, Giampiero; Federico, Stephanie
Adenine derivatives as inhibitors of the casein kinase CK1delta enzyme
2024-01-01 Spinaci, Andrea; Lambertucci, Catia; Chang, Cui; Buccioni, Michela; Marucci, Gabriella; Cescon, Eleonora; Federico, Stephanie; Spalluto, Giampiero; Dal Ben, Diego; Volpini, Rosaria
Adenosine Receptor Ligands, Probes, and Functional Conjugates: A 20-Year History of Pyrazolo[4,3-e][1,2,4]Triazolo[1,5-c]Pyrimidines (PTP)
2023-01-01 Prencipe, F.; Da Ros, T.; Cescon, E.; Grieco, I.; Persico, M.; Spalluto, G.; Federico, S.
Advances in Computational Techniques to Study GPCR-Ligand Recognition
2015-01-01 Ciancetta, Antonella; Sabbadin, Davide; Federico, Stephanie; Spalluto, Giampiero; Moro, Stefano
Anticonvulsivanti
2015-01-01 Spalluto, Giampiero; Federico, Stephanie