SCHOEFTNER, Stefan
SCHOEFTNER, Stefan
Dipartimento di Scienze della Vita
Settore BIO/11 - Biologia Molecolare
Docenti di ruolo di IIa fascia
A 'higher order' of telomere regulation: telomere heterochromatin and telomeric RNAs
2009-01-01 Schoeftner, Stefan; Blasco Maria, A.
A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases
2008-01-01 Benetti, Roberta; Gonzalo, Susana; Jaco, Isabel; Munoz, Purificacion; Gonzalez, Susana; Schoeftner, Stefan; Murchison, Elizabeth; Andl, Thomas; Chen, Taiping; Klatt, Peter; Li, En; Serrano, Manuel; Millar, Sarah; Hannon, Gregory; Blasco Maria, A.
Altered telomere homeostasis and resistance to skin carcinogenesis in Suv39h1 transgenic mice
2015-01-01 Petti, Eleonora; Jordi, Fabian; Buemi, Valentina; Dinami, Roberto; Benetti, Roberta; Blasco, Maria A; Schoeftner, Stefan
An Oct4-pRB axis, controlled by MiR-335, integrates stem cell self-renewal and cell cycle control
2013-01-01 Schoeftner, Stefan; Scarola, Michele; Comisso, Elisa; Schneider, Claudio; Benetti, Roberta
Breast cancer organoids model patient‐specific response to drug treatment
2020-01-01 Campaner, E.; Zannini, A.; Santorsola, M.; Bonazza, D.; Bottin, C.; Cancila, V.; Tripodo, C.; Bortul, M.; Zanconati, F.; Schoeftner, S.; Del Sal, G.
Brevetto Internazionale WO2021/240340A1: Titolo: "Pharmacological composition for the chemical inhibition of TGS1 in the therapeutic treatment of telomeropathies" Inventori: Grazia Daniela Raffa, Stefano Cacchione, Stefan Schoeftner (Università La Sapienza, Roma; Università degli Studi di Trieste)
2021-01-01 Daniela Raffa, Grazia; Cacchione, Stefano; Schoeftner, Stefan
Chromatin regulation and non-coding RNAs at mammalian telomeres
2010-01-01 Schoeftner, Stefan; Blasco Maria, A.
Chromatin Regulation at Parental Gene Promoters by Pseudogene Sense lncRNAs
2021-01-01 Schoeftner, S.; Scarola, M.; Benetti, R.
Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II
2008-01-01 Schoeftner, Stefan; Blasco Maria, A.
Epigenetic silencing of miR-296 and miR-512 ensures hTERT dependent apoptosis protection and telomere maintenance in basal-type breast cancer cells
2017-01-01 Dinami, R; Buemi, V; Sestito, R; Zappone, A; Ciani, Y; Mano, M; Petti, E; Sacconi, A; Blandino, G; Giacca, M; Piazza, S; Benetti, R; Schoeftner, S
Epigenetic silencing of Oct4 by a complex containing SUV39H1 and Oct4 pseudogene lncRNA
2015-01-01 Scarola, Michele; Comisso, Elisa; Pascolo, Rhena; Chiaradia, Riccardo; Marion, Rosa Maria; Schneider, Claudio; Blasco, Maria A; Schoeftner, Stefan; Benetti, Roberta
FUS-dependent loading of SUV39H1 to OCT4 pseudogene-lncRNA programs a silencing complex with OCT4 promoter specificity
2020-01-01 Scarola, M.; Comisso, E.; Rosso, M.; Del Sal, G.; Schneider, C.; Schoeftner, S.; Benetti, R.
Loss of Human TGS1 Hypermethylase Promotes Increased Telomerase RNA and Telomere Elongation
2020-01-01 Chen, Lu; Roake, Caitlin M; Galati, Alessandra; Bavasso, Francesca; Micheli, Emanuela; Saggio, Isabella; Schoeftner, Stefan; Cacchione, Stefano; Gatti, Maurizio; Artandi, Steven E; Raffa, Grazia D
Mammalian Rap1 controls telomere function and gene expression through binding to telomeric and extratelomeric sites
2010-01-01 Martinez, Paula; Thanasoula, Maria; Carlos Ana, R.; Gomez Lopez, Gonzalo; Tejera Agueda, M.; Schoeftner, Stefan; Dominguez, Orlando; Pisano David, G. .; Tarsounas, Madalena; Blasco Maria, A.
microRNAs control the function of telomeres in cancer
2014-01-01 Dinami, Roberto; Petti, Eleonora; Sestito, Rosanna; Benetti, Roberta; Schoeftner, Stefan
miR-155 drives telomere fragility in human breast cancer by targeting TRF1
2014-01-01 Dinami, Roberto; Ercolani, Cristiana; Petti, Eleonora; Piazza, Silvano; Ciani, Yari; Sestito, Rosanna; Sacconi, Andrea; Biagioni, Francesca; Le Sage, Carlos; Agami, Reuven; Benetti, Roberta; Mottolese, Marcella; Schneider, Claudio; Blandino, Giovanni; Schoeftner, Stefan
MiR-182-3p targets TRF2 and impairs tumor growth of triple-negative breast cancer
2023-01-01 Dinami, Roberto; Pompili, Luca; Petti, Eleonora; Porru, Manuela; D'Angelo, Carmen; Di Vito, Serena; Rizzo, Angela; Campani, Virginia; De Rosa, Giuseppe; Bruna, Alejandra; Serra, Violeta; Mano, Miguel; Giacca, Mauro; Leonetti, Carlo; Ciliberto, Gennaro; Tarsounas, Madalena; Stoppacciaro, Antonella; Schoeftner, Stefan; Biroccio, Annamaria
miR-335 Directly Targets Rb1 (pRb/p105) in a Proximal Connection to p53-Dependent Stress Response
2010-01-01 Scarola, Michele; Schoeftner, Stefan; Schneider, Claudio; Benetti, Roberta
Novel diagnostic and therapeutic agent
2010-01-01 Schoeftner, Stefan; Maria, Blasco A.
OCT4 controls mitotic stability and inactivates the RB tumor suppressor pathway to enhance ovarian cancer aggressiveness
2017-01-01 Comisso, Elisa; Scarola, M; Rosso, Massimo; Piazza, S; Marzinotto, S; Ciani, Yari; Orsaria, M; Mariuzzi, L; Schneider, Claudio; Schoeftner, Stefan; Benetti, R.