SCAGGIANTE, BRUNA
 Distribuzione geografica
Continente #
EU - Europa 28.677
NA - Nord America 10.164
AS - Asia 5.416
SA - Sud America 570
AF - Africa 127
Continente sconosciuto - Info sul continente non disponibili 27
OC - Oceania 25
Totale 45.006
Nazione #
IT - Italia 22.443
US - Stati Uniti d'America 9.994
SG - Singapore 1.880
PL - Polonia 1.369
CN - Cina 1.355
SE - Svezia 813
FR - Francia 747
UA - Ucraina 566
DE - Germania 562
VN - Vietnam 559
HK - Hong Kong 483
BR - Brasile 450
GB - Regno Unito 413
KR - Corea 383
NL - Olanda 333
FI - Finlandia 308
RU - Federazione Russa 255
TR - Turchia 228
CH - Svizzera 168
IN - India 141
BG - Bulgaria 139
IE - Irlanda 133
CA - Canada 96
ES - Italia 81
BE - Belgio 72
RO - Romania 52
BD - Bangladesh 46
MA - Marocco 45
MX - Messico 44
JP - Giappone 42
IQ - Iraq 37
AR - Argentina 34
IR - Iran 33
AL - Albania 32
AT - Austria 30
SA - Arabia Saudita 28
ZA - Sudafrica 27
EU - Europa 26
ID - Indonesia 24
PK - Pakistan 23
AU - Australia 22
PT - Portogallo 22
DK - Danimarca 20
EC - Ecuador 20
GR - Grecia 17
JO - Giordania 16
TH - Thailandia 15
UZ - Uzbekistan 15
SI - Slovenia 14
CZ - Repubblica Ceca 13
IL - Israele 12
VE - Venezuela 12
CO - Colombia 11
EG - Egitto 11
MY - Malesia 11
PE - Perù 11
PY - Paraguay 11
CL - Cile 10
AE - Emirati Arabi Uniti 9
AZ - Azerbaigian 9
DZ - Algeria 9
KE - Kenya 9
LT - Lituania 9
RS - Serbia 9
SN - Senegal 9
PH - Filippine 8
HR - Croazia 7
NP - Nepal 7
SK - Slovacchia (Repubblica Slovacca) 7
TW - Taiwan 7
HU - Ungheria 6
KZ - Kazakistan 6
LU - Lussemburgo 6
SM - San Marino 6
GE - Georgia 5
MD - Moldavia 5
NI - Nicaragua 5
OM - Oman 5
UY - Uruguay 5
BH - Bahrain 4
BY - Bielorussia 4
CR - Costa Rica 4
EE - Estonia 4
JM - Giamaica 4
LB - Libano 4
LV - Lettonia 4
MO - Macao, regione amministrativa speciale della Cina 4
TN - Tunisia 4
TT - Trinidad e Tobago 4
DO - Repubblica Dominicana 3
GD - Grenada 3
PA - Panama 3
BA - Bosnia-Erzegovina 2
BO - Bolivia 2
CI - Costa d'Avorio 2
GY - Guiana 2
HN - Honduras 2
KG - Kirghizistan 2
KW - Kuwait 2
LK - Sri Lanka 2
Totale 44.970
Città #
Rome 1.201
Warsaw 1.199
Milan 1.192
Singapore 1.102
Ann Arbor 1.000
Ashburn 974
Chandler 721
Trieste 702
Woodbridge 676
Fairfield 545
Houston 529
San Jose 528
Jacksonville 507
Hong Kong 457
Hefei 398
Seoul 372
Naples 340
Wilmington 320
Beijing 298
Florence 248
Turin 222
Boardman 221
Seattle 219
Bologna 218
Padova 217
Princeton 214
Izmir 190
Dallas 177
Palermo 174
Cambridge 169
Ho Chi Minh City 164
Chicago 153
Los Angeles 147
Hanoi 141
Napoli 140
Sofia 133
Columbus 128
Dublin 126
Bari 123
Santa Clara 122
Lauterbourg 117
Torino 113
Genoa 112
Moscow 112
The Dalles 112
Dearborn 107
Zgierz 107
Brescia 101
Catania 99
Helsinki 98
Udine 86
Cagliari 81
Verona 80
Venezia 79
London 73
Buffalo 72
Munich 72
Perugia 68
Frankfurt am Main 67
Bergamo 63
Treviso 58
Amsterdam 57
Brussels 57
Düsseldorf 57
Venice 57
New York 56
Redwood City 55
Duino-Aurisina 52
Council Bluffs 51
São Paulo 49
Caserta 48
Pescara 47
Monza 46
Genova 44
Messina 44
Mountain View 43
Como 40
Reggio Calabria 38
San Diego 37
Toronto 37
Vicenza 37
Casablanca 36
Turku 36
Lucca 35
Modena 35
Orem 35
Pisa 35
Redmond 35
Falls Church 32
Mestre 32
Sassari 32
Shanghai 32
Ancona 31
North Bergen 31
Salerno 31
Taranto 31
Tokyo 31
Latina 29
Chennai 28
Siena 28
Totale 20.151
Nome #
Valutazione quantitativa di Ki-67 nel carcinoma mammario: comparazione tra lettura al microscopio ottico e lettura con analizzatore automatico 21.794
VALUTAZIONE DEL TOUCH-IMPRINT CITOLOGICO NEL TRATTAMENTO DEL CANCRO DELLA MAMMELLA 1.342
Studio pilota sul ruolo dell’allattamento e dei fattori riproduttivi nel rischio dei carcinomi mammari Luminali nelle donne in premenopausa 447
Analisi dei tempi d’attesa tra le varie fasi di gestione dei carcinomi mammari screening-detected a Trieste nel biennio 2013-2014: come si può migliorare? 446
Breastfeeding: a reproductive factor able to reduce the risk of luminal B breast cancer in premenopausal White women 398
NEODUCTGENESIS AS A PROGNOSTIC MARKER IN “DUCTAL” CARCINOMA IN SITU OF THE BREAST 398
GT75 aptamer against eukaryotic elongation factor 1A as potential anticancer drug for castrate-resistant prostate cancer (CRPC). 392
Cell-free DNA integrity for the monitoring of breast cancer: Future perspectives? 387
Current status of PI3K-mTOR inhibition in hormone-receptor positive, HER2-negative breast cancer 334
Therapeutic potential of Nucleic acid-based drugs in coronary hyper-proliferative vascular diseases 306
Breastfeeding is an additional protective factor for breast cancer among women living in the metropolitan area of Trieste. 304
Therapeutic potential and delivery strategies for nucleic acid-based drugs 300
Parità e Allattamento quali fattori protettivi di carcinoma mammario nelle donne triestine 300
Novel Lipid and Polymeric Materials as Delivery Systems for Nucleic Acid Based Drugs 280
Elevated levels of eEF1A2 protein expression in triple negative breast cancer relate with poor prognosis 277
The relevance of chemobrain in breast cancer survivors: An Italian exploratory study to measure incidence and psycho-social impact 277
Cell-free DNA analysis in healthy individuals by next-generation sequencing: a proof of concept and technical validation study. 270
Current strategies to improve the efficacy and the delivery of nucleic acid based drugs 264
Aptameric GT oligomers need to be complexed to ethoxylated polyethylenimine as pre-paired duplexes to efficiently exert their cytotoxic activity in human lymphoblastic cancer cells 262
Dissecting the role of the elongation factor 1A isoforms in hepatocellular carcinoma cells by liposome-mediated delivery of siRNAs 256
Membranes in Drug Delivery 255
Analisi delle caratteristiche dei carcinomi d’intervallo e screening detected a 10 anni dall’attivazione del programma di screening mammografico regionale del Friuli Venezia-Giulia nella provincia di Trieste 255
Bortezomib arrests the proliferation of hepatocellular carcinoma cells HepG2 and JHH6 by differentially affecting E2F1, p21 and p27 levels. 250
Aptamer targeting of the elongation factor 1A impairs hepatocarcinoma cells viability and potentiates bortezomib and idarubicin effects 250
Effect of cations on purine.purine.pyrimidine triple helix formation in mixed valence salt solutions. 248
"Human cancer cell lines growth inhibition by GTn oligodeoxyribonucleotides recognizing single stranded DNA-binding proteins" 247
Diagnostic and prognostic role of eEF1A in chronic lymphocytic leukaemia 244
Caratteristiche dei carcinomi screening-detected a 6 anni dall’ avvio del programma di screening mammografico a Trieste 238
A rapid and specific method to simultaneously quantify eukaryoticelongation factor 1A1 and A2 protein levels in cancer cells 238
Translation Elongation 233
An update of aberrant methylation detection on circulating cell-free DNA as a tool to improve prostate cancer diagnosis and prognosis 233
Effects of E2F1-cyclinE1-E2 circuit down-regulation in hepatocellular carcinoma cells 232
Aptamers as nano-targeting delivery devices or anti-cancer drugs for fighting tumours 227
Dissecting the expression of EEF1A1/A2 genes in human prostate cancer cells: the potential od EEF1A2 as a hallmark for prostate transformation and progression 226
A siRNA targeted against SRF reduce hepatocellular carcinoma cell proliferation, showing its potential use in the growth inhibition of this type of tumor 210
A siRNA targeted against SRF reduce hepatocellular carcinoma cell proliferation, showing its potential use in the growth inhibition of this type of tumor 203
Effects of eEF1A1 targeting by aptamer/siRNA in chronic lymphocytic leukaemia cells 203
PDPG Polymer as a targeted delivery system for siRNAs to hepatocellular carcinoma cells 202
The expression levels of the translational factors eEF1A 1/2 correlate with cell growth but not apoptosis in hepatocellular carcinoma cell lines with different differentiation grade 201
Novel hepatocellular carcinoma molecules with prognostic and therapeutic potentials 199
Ruolo della FNAC nel programma di Screening Mammografico a Trieste 197
Evaluation of the contribution of the elongational factor 1 A isoforms in hepatocellular carcinoma celss growth 193
EEF1A1 (eukaryotic translation elongation factor 1 alpha 1) (6q.13) Atlas Genet Cytogenet Oncol Haematol 14 (4):660-670. 192
Anxiety stress and nociceptive responses in mice. 191
Epigenetic and miRNAs dysregulation in prostate cancer: the role of nutraceuticals. 188
Overexpression of the elongation factor 1A1 relates to muscle proteolysis and proapoptotic p66(ShcA) gene transcription in hypercatabolic trauma patients. 187
Bortezomib effect of E2F and cyclin family members in human hepatocellular carcinoma cell lines 187
Protein phosphorylation and neutrophil activation 181
Diurnal changes of tonic nociceptive responses in mice: evidence for a proalgesic role for melatonin 180
Formation of triple helices at irregular RY sites located in the critical position in the human bcr promoter. 178
Improving siRNA Bio-Distribution and Minimizing Side Effects 177
Evaluation of circulating cell-free DNA and its integrity as a potential predictive biomarker of breast cancer onset: A pilot study 173
Impact of psychosocial, behavioral and lifestyle factors on subjective cognitive complaints and perceived quality of life in a large cohort of Italian breast cancer patients 171
Aptamers as targeting delivery devices or anti-cancer drugs for fighting tumors 170
BCG-Unresponsive Non-Muscle-Invasive Bladder Cancer: Current Treatment Landscape and Novel Emerging Molecular Targets 164
“Alpha-anomeric configuration of GT oligodeoxynucleotide leads to loss of specific aptameric and cytotoxic properties retained by the Beta-anomeric analog” 161
Nucleic Acids-based Aptamers and their applications 161
Targeted delivery of siRNAs against hepatocellular carcinoma-related genes by a galactosylated polyaspartamide copolymer 160
Xenograft zebrafish models for the development of novel anti-hepatocellular carcinoma molecules 159
“The expression levels of the translational factors eEF1A1/2 correlate with the cell growth but not apoptosis in hepatocellular carcinoma cell lines with different differentiation grade” 157
The Role of the eEF1A Family in Human Cancers 157
Two-Dimensional Enzyme Diffusion Demonstrated in Laterally Confined DNA Monolayers 157
High eEF1A1 Protein Levels Mark Aggressive Prostate Cancers and the In Vitro Targeting of eEF1A1 Reveals the eEF1A1–Actin Complex as a New Potential Target for Therapy 156
The targeting of the elongation factor 1A by a DNA aptamer impairs the viability of hepatocarcinoma cells 155
Attivazione dell'espressione di elongation factor 1A2 nei tumori prostatici 152
Triple-helix forming oligodeoxyribonucleotide, inhibiting mdr1 transcription may reduce mdr1 gene amplification level in multidrug-resistant leukaemic cell line 150
null 150
"Reduction of mdr1 gene amplification in human multidrug resistant LoVo dX cellline is promoted by triple-helix forming oligonucleotides" 149
SiRNAs targeted against cyclin E1, cyclin E2 and E2F1 down regulate the growth of Hepatocellular Carcinoma showing their potential use in the prevention of this type of tumor 149
A pivotal study in human prostate cancer tissues and cell lines to measure the expression levels of eukaryotic Elongation Factor 1A proteins and the effect of a nucleic acid-based GT75 aptamer 149
An Overview of Circulating Cell-Free Nucleic Acids in Diagnosis and Prognosis of Triple-Negative Breast Cancer 148
An Overview of siRNA Delivery Strategies for Urological Cancers 148
Role of E2F1-cycline1-cycline2 circuit in hepatocellular carcinoma cell proliferation and therapeutic potential of its down-regulation by siRNAs 146
In Vitro and In Vivo Evaluation of the Effects of Drug 2c and Derivatives on Ovarian Cancer Cells 145
Repeated Implantations of human amniotic epithelial cells as a curative therapy of Niemann-Pick disease 144
Medicine, Biology and mathematics 142
Scalp cooling system to prevent alopecia: Effectiveness, psychological effects and feasibility 141
“Impianto di cellule epiteliali amniotiche umane crioconservate in un soggetto affetto da malattia di Niemann-Pick tipo B.” 140
Targeting Non-Coding RNAs for the Development of Novel Hepatocellular Carcinoma Therapeutic Approaches 139
null 136
A Case–Control Study by ddPCR of ALU 260/111 and LINE-1 266/97 Copy Number Ratio in Circulating Cell-Free DNA in Plasma Revealed LINE-1 266/97 as a Potential Biomarker for Early Breast Cancer Detection 136
“The anti-gene DNA strategy by triple helix directed oligodeoxyribonucleotides to modulate human mdr1 gene expression.” 135
Interaction of G-rich GT oligonucleotides with nuclear-associated eEF1A is correlated with their antiproliferative effect in haematopoietic human cancer cell lines. 132
Small, antibacterial and large, inactive peptides of neutrophil granules share immunoreactivity to a monoclonal antibody. 131
Potential Application Of Proteasome Inhibitor Bortezomib For Treatment Of Hepatocellular Carcinoma 131
“Effect of phosphorotioate modifications on the GTn oligodeoxynucleotide ability to recognise the single stranded DNA binding proteins specifically related to the human cancer cellular growth inhibition” 129
Effect of oligomer length and base substitutions on the cytotoxic activity and specific nuclear protein recognition of GTn oligonucleotides in the human leukemic CCRF-CEM cell line.” 128
Identification of nuclear elongation factor 1 alpha as single-stranded DNA-binding protein specifically recognising GT oligodeoxynucleotides that exert a selective human cancer cell growth inhibition 128
“Increase of therapeutic index of doxorubicin and vinblastine by aptameric oligonucleotide in human T-lymphoblastic drug-sensitive and multidrug-resistant cells.” 127
Evaluation of bortezomib impact on cell-cycle related genes in the hepatocellular carcinoma cell lines hepg2 and jhh6 by means of microarray analysis 127
dGT sequences specifically and selectively inhibiting growth of human cancer cell lines, recognise single-stranded DNA-binding proteins 125
Potential Application Of Proteasome Inhibitor Bortezomib For the Treatment Of Hepatocellular Carcinoma 124
Angiogenesis and Ovarian Cancer: What Potential Do Different Subtypes of Circulating Endothelial Cells Have for Clinical Application? 122
Programmi di mindfulness online per pazienti oncologici: quali benefici nei percorsi di cura. Una revisione della letteratura e lo stato dell'arte 121
“Correlation between cytotoxic effect and binding to nuclear proteins of oligomeric d(GT)n sequences in human cancer CCRF-CEM cell line.” 121
Ethoxylated polyethylenimine successfully enhances the cytotoxic activity of GT oligomers targeted to specific nuclear proteins in human T-Lymphoblastic cancer cells. 121
EEF1A1 (eukaryotic translation elongation factor 1 alpha 1). Atlas Genet Cytogenet Oncol Haematol. May 2009 . 119
null 119
The more basic isoform of eEF1A relates to tumour cell phenotype and is modulated by hyper-proliferative/differentiating stimuli in normal lymphocytes and CCRF-CEM T-lymphoblasts 119
Triple-stranded DNA: formation, stability and application in biology.” 118
Totale 42.621
Categoria #
all - tutte 86.755
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 86.755


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021836 0 0 0 0 0 0 0 0 0 359 196 281
2021/20222.959 183 185 174 304 164 192 150 221 326 271 251 538
2022/20235.954 447 503 469 551 450 647 349 572 561 338 541 526
2023/20244.722 506 446 393 367 413 301 504 547 111 406 392 336
2024/20254.714 324 343 454 397 441 477 298 300 524 409 377 370
2025/20266.792 815 478 604 672 555 693 957 254 884 880 0 0
Totale 45.627