SCAGGIANTE, BRUNA
 Distribuzione geografica
Continente #
EU - Europa 24.483
NA - Nord America 7.094
AS - Asia 1.062
Continente sconosciuto - Info sul continente non disponibili 26
SA - Sud America 20
OC - Oceania 18
AF - Africa 12
Totale 32.715
Nazione #
IT - Italia 19.927
US - Stati Uniti d'America 7.055
PL - Polonia 1.202
SE - Svezia 787
UA - Ucraina 542
FR - Francia 456
CN - Cina 426
DE - Germania 349
HK - Hong Kong 236
GB - Regno Unito 228
TR - Turchia 210
FI - Finlandia 201
CH - Svizzera 161
BG - Bulgaria 136
IE - Irlanda 119
BE - Belgio 65
ES - Italia 58
RU - Federazione Russa 46
IN - India 44
RO - Romania 42
CA - Canada 37
NL - Olanda 31
VN - Vietnam 29
AL - Albania 28
EU - Europa 26
KR - Corea 25
SG - Singapore 23
AU - Australia 17
BR - Brasile 17
DK - Danimarca 16
IR - Iran 16
PT - Portogallo 15
SI - Slovenia 11
AT - Austria 9
JP - Giappone 8
GR - Grecia 7
CZ - Repubblica Ceca 6
HR - Croazia 6
RS - Serbia 6
SM - San Marino 6
SN - Senegal 6
TH - Thailandia 6
IL - Israele 5
JO - Giordania 5
LU - Lussemburgo 5
MY - Malesia 5
MD - Moldavia 4
MO - Macao, regione amministrativa speciale della Cina 4
PK - Pakistan 4
SA - Arabia Saudita 4
EG - Egitto 3
GE - Georgia 3
HU - Ungheria 3
AE - Emirati Arabi Uniti 2
CL - Cile 2
EE - Estonia 2
ID - Indonesia 2
LV - Lettonia 2
MT - Malta 2
MX - Messico 2
SK - Slovacchia (Repubblica Slovacca) 2
AM - Armenia 1
BA - Bosnia-Erzegovina 1
CF - Repubblica Centrafricana 1
IQ - Iraq 1
KZ - Kazakistan 1
LB - Libano 1
MW - Malawi 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PE - Perù 1
TW - Taiwan 1
VA - Santa Sede (Città del Vaticano) 1
ZA - Sudafrica 1
Totale 32.715
Città #
Warsaw 1.159
Rome 986
Ann Arbor 983
Milan 939
Chandler 710
Woodbridge 666
Trieste 589
Fairfield 541
Houston 516
Jacksonville 499
Ashburn 443
Wilmington 317
Naples 239
Hong Kong 227
Princeton 212
Seattle 210
Padova 194
Izmir 189
Florence 184
Turin 175
Bologna 170
Cambridge 162
Palermo 152
Napoli 140
Sofia 131
Beijing 119
Torino 113
Dublin 112
Bari 106
Dearborn 106
Brescia 87
Catania 87
Udine 82
Venezia 79
Boardman 78
Genoa 71
Dallas 70
Cagliari 65
Verona 62
Bergamo 57
Redwood City 55
Duino-Aurisina 51
Brussels 50
Perugia 50
Caserta 47
Treviso 46
Genova 44
Mountain View 43
Como 40
Messina 40
Venice 40
Monza 38
Pescara 37
San Diego 37
Vicenza 36
Redmond 35
Falls Church 32
Helsinki 32
Mestre 31
Sassari 30
Pisa 29
Reggio Calabria 29
Taranto 29
Ancona 28
Latina 26
Nanjing 26
Reggio Nell'emilia 26
Salerno 26
Bremen 25
Catanzaro 25
Grafing 25
Parma 25
Modena 24
Scafati 24
Siena 24
Pavia 23
Torre Del Greco 23
Dong Ket 22
Foggia 22
Livorno 22
Shanghai 22
Toronto 22
Düsseldorf 21
Jinan 21
Ravenna 21
Ferrara 20
Hefei 20
Lucca 20
Novara 19
Pignone 19
Prato 19
Trento 19
Abbiategrasso 18
Barcelona 18
Chicago 18
Columbus 18
Los Angeles 18
Seoul 18
Reggio Emilia 17
Washington 17
Totale 13.729
Nome #
Valutazione quantitativa di Ki-67 nel carcinoma mammario: comparazione tra lettura al microscopio ottico e lettura con analizzatore automatico 19.493
VALUTAZIONE DEL TOUCH-IMPRINT CITOLOGICO NEL TRATTAMENTO DEL CANCRO DELLA MAMMELLA 1.070
Analisi dei tempi d’attesa tra le varie fasi di gestione dei carcinomi mammari screening-detected a Trieste nel biennio 2013-2014: come si può migliorare? 350
Studio pilota sul ruolo dell’allattamento e dei fattori riproduttivi nel rischio dei carcinomi mammari Luminali nelle donne in premenopausa 337
GT75 aptamer against eukaryotic elongation factor 1A as potential anticancer drug for castrate-resistant prostate cancer (CRPC). 321
Breastfeeding: a reproductive factor able to reduce the risk of luminal B breast cancer in premenopausal White women 316
Cell-free DNA integrity for the monitoring of breast cancer: Future perspectives? 312
NEODUCTGENESIS AS A PROGNOSTIC MARKER IN “DUCTAL” CARCINOMA IN SITU OF THE BREAST 264
Current status of PI3K-mTOR inhibition in hormone-receptor positive, HER2-negative breast cancer 246
Cell-free DNA analysis in healthy individuals by next-generation sequencing: a proof of concept and technical validation study. 226
Elevated levels of eEF1A2 protein expression in triple negative breast cancer relate with poor prognosis 223
Therapeutic potential of Nucleic acid-based drugs in coronary hyper-proliferative vascular diseases 217
Therapeutic potential and delivery strategies for nucleic acid-based drugs 196
Parità e Allattamento quali fattori protettivi di carcinoma mammario nelle donne triestine 190
Current strategies to improve the efficacy and the delivery of nucleic acid based drugs 183
Breastfeeding is an additional protective factor for breast cancer among women living in the metropolitan area of Trieste. 183
Novel Lipid and Polymeric Materials as Delivery Systems for Nucleic Acid Based Drugs 168
Translation Elongation 167
Effect of cations on purine.purine.pyrimidine triple helix formation in mixed valence salt solutions. 166
Membranes in Drug Delivery 162
Analisi delle caratteristiche dei carcinomi d’intervallo e screening detected a 10 anni dall’attivazione del programma di screening mammografico regionale del Friuli Venezia-Giulia nella provincia di Trieste 161
Aptameric GT oligomers need to be complexed to ethoxylated polyethylenimine as pre-paired duplexes to efficiently exert their cytotoxic activity in human lymphoblastic cancer cells 158
Bortezomib arrests the proliferation of hepatocellular carcinoma cells HepG2 and JHH6 by differentially affecting E2F1, p21 and p27 levels. 155
The expression levels of the translational factors eEF1A 1/2 correlate with cell growth but not apoptosis in hepatocellular carcinoma cell lines with different differentiation grade 153
null 150
Dissecting the expression of EEF1A1/A2 genes in human prostate cancer cells: the potential od EEF1A2 as a hallmark for prostate transformation and progression 145
Dissecting the role of the elongation factor 1A isoforms in hepatocellular carcinoma cells by liposome-mediated delivery of siRNAs 145
"Human cancer cell lines growth inhibition by GTn oligodeoxyribonucleotides recognizing single stranded DNA-binding proteins" 143
Aptamer targeting of the elongation factor 1A impairs hepatocarcinoma cells viability and potentiates bortezomib and idarubicin effects 138
Effects of E2F1-cyclinE1-E2 circuit down-regulation in hepatocellular carcinoma cells 137
null 136
Improving siRNA Bio-Distribution and Minimizing Side Effects 135
Epigenetic and miRNAs dysregulation in prostate cancer: the role of nutraceuticals. 132
Overexpression of the elongation factor 1A1 relates to muscle proteolysis and proapoptotic p66(ShcA) gene transcription in hypercatabolic trauma patients. 127
Aptamers as nano-targeting delivery devices or anti-cancer drugs for fighting tumours 126
Diagnostic and prognostic role of eEF1A in chronic lymphocytic leukaemia 125
The relevance of chemobrain in breast cancer survivors: An Italian exploratory study to measure incidence and psycho-social impact 125
Diurnal changes of tonic nociceptive responses in mice: evidence for a proalgesic role for melatonin 124
A rapid and specific method to simultaneously quantify eukaryoticelongation factor 1A1 and A2 protein levels in cancer cells 124
Novel hepatocellular carcinoma molecules with prognostic and therapeutic potentials 123
Caratteristiche dei carcinomi screening-detected a 6 anni dall’ avvio del programma di screening mammografico a Trieste 119
null 119
A siRNA targeted against SRF reduce hepatocellular carcinoma cell proliferation, showing its potential use in the growth inhibition of this type of tumor 116
EEF1A1 (eukaryotic translation elongation factor 1 alpha 1) (6q.13) Atlas Genet Cytogenet Oncol Haematol 14 (4):660-670. 116
Anxiety stress and nociceptive responses in mice. 114
An update of aberrant methylation detection on circulating cell-free DNA as a tool to improve prostate cancer diagnosis and prognosis 111
null 111
Two-Dimensional Enzyme Diffusion Demonstrated in Laterally Confined DNA Monolayers 110
Evaluation of the contribution of the elongational factor 1 A isoforms in hepatocellular carcinoma celss growth 107
“Alpha-anomeric configuration of GT oligodeoxynucleotide leads to loss of specific aptameric and cytotoxic properties retained by the Beta-anomeric analog” 106
SiRNAs targeted against cyclin E1, cyclin E2 and E2F1 down regulate the growth of Hepatocellular Carcinoma showing their potential use in the prevention of this type of tumor 106
“The expression levels of the translational factors eEF1A1/2 correlate with the cell growth but not apoptosis in hepatocellular carcinoma cell lines with different differentiation grade” 105
A siRNA targeted against SRF reduce hepatocellular carcinoma cell proliferation, showing its potential use in the growth inhibition of this type of tumor 105
The Role of the eEF1A Family in Human Cancers 104
Triple-helix forming oligodeoxyribonucleotide, inhibiting mdr1 transcription may reduce mdr1 gene amplification level in multidrug-resistant leukaemic cell line 103
Effects of eEF1A1 targeting by aptamer/siRNA in chronic lymphocytic leukaemia cells 102
PDPG Polymer as a targeted delivery system for siRNAs to hepatocellular carcinoma cells 102
Repeated Implantations of human amniotic epithelial cells as a curative therapy of Niemann-Pick disease 101
Medicine, Biology and mathematics 101
Protein phosphorylation and neutrophil activation 100
The targeting of the elongation factor 1A by a DNA aptamer impairs the viability of hepatocarcinoma cells 100
Ruolo della FNAC nel programma di Screening Mammografico a Trieste 99
Role of E2F1-cycline1-cycline2 circuit in hepatocellular carcinoma cell proliferation and therapeutic potential of its down-regulation by siRNAs 98
null 97
Evaluation of bortezomib impact on cell-cycle related genes in the hepatocellular carcinoma cell lines hepg2 and jhh6 by means of microarray analysis 88
Potential Application Of Proteasome Inhibitor Bortezomib For Treatment Of Hepatocellular Carcinoma 88
Potential Application Of Proteasome Inhibitor Bortezomib For the Treatment Of Hepatocellular Carcinoma 84
Evaluation of circulating cell-free DNA and its integrity as a potential predictive biomarker of breast cancer onset: A pilot study 84
Identification of nuclear elongation factor 1 alpha as single-stranded DNA-binding protein specifically recognising GT oligodeoxynucleotides that exert a selective human cancer cell growth inhibition 83
Effect of oligomer length and base substitutions on the cytotoxic activity and specific nuclear protein recognition of GTn oligonucleotides in the human leukemic CCRF-CEM cell line.” 80
Small, antibacterial and large, inactive peptides of neutrophil granules share immunoreactivity to a monoclonal antibody. 79
“Impianto di cellule epiteliali amniotiche umane crioconservate in un soggetto affetto da malattia di Niemann-Pick tipo B.” 75
Attivazione dell'espressione di elongation factor 1A2 nei tumori prostatici 75
“Effect of phosphorotioate modifications on the GTn oligodeoxynucleotide ability to recognise the single stranded DNA binding proteins specifically related to the human cancer cellular growth inhibition” 74
Ethoxylated polyethylenimine successfully enhances the cytotoxic activity of GT oligomers targeted to specific nuclear proteins in human T-Lymphoblastic cancer cells. 74
null 73
Triple-stranded DNA: formation, stability and application in biology.” 72
dGT sequences specifically and selectively inhibiting growth of human cancer cell lines, recognise single-stranded DNA-binding proteins 72
In vivo specific loss of DNA amplification by intermolecular triple-helix forming oligodeoxyribonucleotides.” 72
EEF1A1 (eukaryotic translation elongation factor 1 alpha 1). Atlas Genet Cytogenet Oncol Haematol. May 2009 . 72
The more basic isoform of eEF1A relates to tumour cell phenotype and is modulated by hyper-proliferative/differentiating stimuli in normal lymphocytes and CCRF-CEM T-lymphoblasts 72
High eEF1A1 Protein Levels Mark Aggressive Prostate Cancers and the In Vitro Targeting of eEF1A1 Reveals the eEF1A1–Actin Complex as a New Potential Target for Therapy 72
Circulating cell-free nucleic acids as prognostic and therapy predictive tools for metastatic castrate-resistant prostate cancer 69
“Correlation between cytotoxic effect and binding to nuclear proteins of oligomeric d(GT)n sequences in human cancer CCRF-CEM cell line.” 68
“The anti-gene DNA strategy by triple helix directed oligodeoxyribonucleotides to modulate human mdr1 gene expression.” 66
“Alpha-anomeric configuration of GT-oligodeoxynucleotide leads to loss of the specific aptameric and cytotoxic properties retained by the beta-anomeric analogue.” 65
GT75 oligonucleotide as therapeutically new antitumoral agent and new aptamer for diagnostic u 64
siRNA, Ribozyme and Aptamer Oligonucleotides as Molecular Tools for the Control of Cell Proliferation in the Perspective of Supporting Therapies 63
“Increase of therapeutic index of doxorubicin and vinblastine by aptameric oligonucleotide in human T-lymphoblastic drug-sensitive and multidrug-resistant cells.” 61
Scalp cooling system to prevent alopecia: Effectiveness, psychological effects and feasibility 61
“Effect of phosphorothioate modifications on the ability of GTn oligodeoxynucleotides to specifically recognize single-stranded DNA-binding proteins and to affect human cancer cellular growth.” 59
“Restoring uptake and retention of daunorubicin and idarubicin in P170-related multidrug-resistance cells by low concentration D-verapamil, cyclosporin-A and SDZ PSC 833. ” 59
“Secretion of lysosomal hydrolases by cultured human amnion epithelial cells”. 58
"Reduction of mdr1 gene amplification in human multidrug resistant LoVo dX cellline is promoted by triple-helix forming oligonucleotides" 58
Impact of psychosocial, behavioral and lifestyle factors on subjective cognitive complaints and perceived quality of life in a large cohort of Italian breast cancer patients 56
Xenograft zebrafish models for the development of novel anti-hepatocellular carcinoma molecules 55
“.Identification of different isoforms of eEF1A in the nuclear fraction of human T-lymphoblastic cancer cell lines specifically binding ot aptameric GT oligonucleotides.” 53
“Effect of unmodified triple helix-forming oligodeoxyribonucleotide targeted to human multidrug-resistance gene mdr1 in MDR cancer cells”. 51
Targeted delivery of siRNAs against hepatocellular carcinoma-related genes by a galactosylated polyaspartamide copolymer 51
“Treatment of sphingomyelinase deficiency by repeated implantations of amniotic epithelial cells” 50
Totale 32.560
Categoria #
all - tutte 51.792
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 51.792


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20191.262 0 0 0 0 0 0 0 0 0 0 780 482
2019/20206.115 500 420 580 795 579 739 676 628 365 269 326 238
2020/20213.585 357 286 302 409 310 297 223 269 299 357 196 280
2021/20222.945 183 184 174 301 164 191 150 220 324 270 251 533
2022/20235.929 444 499 467 548 448 644 349 567 558 338 541 526
2023/20243.991 506 445 391 367 411 298 504 541 111 404 13 0
Totale 33.296