SCAGGIANTE, BRUNA
 Distribuzione geografica
Continente #
EU - Europa 25.712
NA - Nord America 7.302
AS - Asia 1.427
Continente sconosciuto - Info sul continente non disponibili 26
SA - Sud America 20
OC - Oceania 19
AF - Africa 17
Totale 34.523
Nazione #
IT - Italia 21.081
US - Stati Uniti d'America 7.262
PL - Polonia 1.205
SE - Svezia 788
UA - Ucraina 543
FR - Francia 461
CN - Cina 460
DE - Germania 366
SG - Singapore 333
GB - Regno Unito 238
HK - Hong Kong 236
TR - Turchia 210
FI - Finlandia 204
CH - Svizzera 162
BG - Bulgaria 136
IE - Irlanda 119
BE - Belgio 65
ES - Italia 60
RU - Federazione Russa 54
IN - India 44
RO - Romania 44
NL - Olanda 39
CA - Canada 38
VN - Vietnam 36
AL - Albania 28
EU - Europa 26
KR - Corea 25
IR - Iran 21
AU - Australia 18
BR - Brasile 17
DK - Danimarca 16
PT - Portogallo 16
GR - Grecia 12
SI - Slovenia 12
JP - Giappone 11
AT - Austria 10
CZ - Repubblica Ceca 10
TH - Thailandia 9
HR - Croazia 7
RS - Serbia 6
SM - San Marino 6
SN - Senegal 6
ZA - Sudafrica 6
IL - Israele 5
JO - Giordania 5
LU - Lussemburgo 5
MY - Malesia 5
SA - Arabia Saudita 5
MD - Moldavia 4
MO - Macao, regione amministrativa speciale della Cina 4
PK - Pakistan 4
EG - Egitto 3
GE - Georgia 3
HU - Ungheria 3
ID - Indonesia 3
AE - Emirati Arabi Uniti 2
CL - Cile 2
EE - Estonia 2
LV - Lettonia 2
MT - Malta 2
MX - Messico 2
SK - Slovacchia (Repubblica Slovacca) 2
TW - Taiwan 2
AM - Armenia 1
BA - Bosnia-Erzegovina 1
CF - Repubblica Centrafricana 1
IQ - Iraq 1
KZ - Kazakistan 1
LB - Libano 1
LT - Lituania 1
MW - Malawi 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PE - Perù 1
VA - Santa Sede (Città del Vaticano) 1
Totale 34.523
Città #
Warsaw 1.159
Rome 1.079
Milan 1.064
Ann Arbor 983
Chandler 710
Woodbridge 666
Trieste 610
Fairfield 541
Houston 516
Jacksonville 499
Ashburn 452
Wilmington 317
Naples 301
Singapore 259
Hong Kong 227
Florence 215
Princeton 212
Seattle 210
Padova 204
Turin 197
Izmir 189
Bologna 185
Palermo 164
Cambridge 162
Napoli 140
Beijing 131
Sofia 131
Bari 114
Torino 113
Dublin 112
Dearborn 106
Brescia 96
Boardman 94
Catania 93
Genoa 92
Dallas 82
Udine 82
Venezia 79
Cagliari 72
Verona 71
Perugia 59
Bergamo 57
Treviso 56
Redwood City 55
Duino-Aurisina 52
Brussels 50
Caserta 48
Santa Clara 48
Genova 44
Monza 44
Mountain View 43
Venice 43
Messina 42
Pescara 41
Como 40
San Diego 37
Vicenza 36
Redmond 35
Reggio Calabria 35
Falls Church 32
Helsinki 32
Pisa 32
Sassari 32
Mestre 31
Salerno 31
Ancona 30
Modena 30
Taranto 30
Latina 29
Lucca 29
Parma 27
Nanjing 26
Reggio Nell'emilia 26
Siena 26
Bremen 25
Catanzaro 25
Grafing 25
Livorno 24
Scafati 24
Pavia 23
Shanghai 23
Torre Del Greco 23
Dong Ket 22
Foggia 22
Toronto 22
Düsseldorf 21
Jinan 21
Novara 21
Prato 21
Ravenna 21
Trento 21
Ferrara 20
Hefei 20
Chicago 19
Los Angeles 19
Pignone 19
Abbiategrasso 18
Barcelona 18
Columbus 18
Legnano 18
Totale 14.590
Nome #
Valutazione quantitativa di Ki-67 nel carcinoma mammario: comparazione tra lettura al microscopio ottico e lettura con analizzatore automatico 20.561
VALUTAZIONE DEL TOUCH-IMPRINT CITOLOGICO NEL TRATTAMENTO DEL CANCRO DELLA MAMMELLA 1.120
Analisi dei tempi d’attesa tra le varie fasi di gestione dei carcinomi mammari screening-detected a Trieste nel biennio 2013-2014: come si può migliorare? 352
Studio pilota sul ruolo dell’allattamento e dei fattori riproduttivi nel rischio dei carcinomi mammari Luminali nelle donne in premenopausa 348
GT75 aptamer against eukaryotic elongation factor 1A as potential anticancer drug for castrate-resistant prostate cancer (CRPC). 325
Breastfeeding: a reproductive factor able to reduce the risk of luminal B breast cancer in premenopausal White women 318
Cell-free DNA integrity for the monitoring of breast cancer: Future perspectives? 312
NEODUCTGENESIS AS A PROGNOSTIC MARKER IN “DUCTAL” CARCINOMA IN SITU OF THE BREAST 274
Current status of PI3K-mTOR inhibition in hormone-receptor positive, HER2-negative breast cancer 255
Cell-free DNA analysis in healthy individuals by next-generation sequencing: a proof of concept and technical validation study. 227
Therapeutic potential of Nucleic acid-based drugs in coronary hyper-proliferative vascular diseases 226
Elevated levels of eEF1A2 protein expression in triple negative breast cancer relate with poor prognosis 225
Breastfeeding is an additional protective factor for breast cancer among women living in the metropolitan area of Trieste. 203
Parità e Allattamento quali fattori protettivi di carcinoma mammario nelle donne triestine 200
Therapeutic potential and delivery strategies for nucleic acid-based drugs 198
Current strategies to improve the efficacy and the delivery of nucleic acid based drugs 183
Translation Elongation 175
Novel Lipid and Polymeric Materials as Delivery Systems for Nucleic Acid Based Drugs 173
Effect of cations on purine.purine.pyrimidine triple helix formation in mixed valence salt solutions. 167
Analisi delle caratteristiche dei carcinomi d’intervallo e screening detected a 10 anni dall’attivazione del programma di screening mammografico regionale del Friuli Venezia-Giulia nella provincia di Trieste 167
Membranes in Drug Delivery 163
"Human cancer cell lines growth inhibition by GTn oligodeoxyribonucleotides recognizing single stranded DNA-binding proteins" 162
Aptameric GT oligomers need to be complexed to ethoxylated polyethylenimine as pre-paired duplexes to efficiently exert their cytotoxic activity in human lymphoblastic cancer cells 160
Bortezomib arrests the proliferation of hepatocellular carcinoma cells HepG2 and JHH6 by differentially affecting E2F1, p21 and p27 levels. 159
The relevance of chemobrain in breast cancer survivors: An Italian exploratory study to measure incidence and psycho-social impact 155
The expression levels of the translational factors eEF1A 1/2 correlate with cell growth but not apoptosis in hepatocellular carcinoma cell lines with different differentiation grade 153
Dissecting the role of the elongation factor 1A isoforms in hepatocellular carcinoma cells by liposome-mediated delivery of siRNAs 153
null 150
Dissecting the expression of EEF1A1/A2 genes in human prostate cancer cells: the potential od EEF1A2 as a hallmark for prostate transformation and progression 148
Caratteristiche dei carcinomi screening-detected a 6 anni dall’ avvio del programma di screening mammografico a Trieste 148
Aptamer targeting of the elongation factor 1A impairs hepatocarcinoma cells viability and potentiates bortezomib and idarubicin effects 147
Overexpression of the elongation factor 1A1 relates to muscle proteolysis and proapoptotic p66(ShcA) gene transcription in hypercatabolic trauma patients. 138
Effects of E2F1-cyclinE1-E2 circuit down-regulation in hepatocellular carcinoma cells 138
null 136
Improving siRNA Bio-Distribution and Minimizing Side Effects 136
Epigenetic and miRNAs dysregulation in prostate cancer: the role of nutraceuticals. 135
Aptamers as nano-targeting delivery devices or anti-cancer drugs for fighting tumours 129
A rapid and specific method to simultaneously quantify eukaryoticelongation factor 1A1 and A2 protein levels in cancer cells 129
Diagnostic and prognostic role of eEF1A in chronic lymphocytic leukaemia 129
An update of aberrant methylation detection on circulating cell-free DNA as a tool to improve prostate cancer diagnosis and prognosis 129
Diurnal changes of tonic nociceptive responses in mice: evidence for a proalgesic role for melatonin 126
Novel hepatocellular carcinoma molecules with prognostic and therapeutic potentials 125
A siRNA targeted against SRF reduce hepatocellular carcinoma cell proliferation, showing its potential use in the growth inhibition of this type of tumor 120
EEF1A1 (eukaryotic translation elongation factor 1 alpha 1) (6q.13) Atlas Genet Cytogenet Oncol Haematol 14 (4):660-670. 119
null 119
Anxiety stress and nociceptive responses in mice. 115
Ruolo della FNAC nel programma di Screening Mammografico a Trieste 115
Two-Dimensional Enzyme Diffusion Demonstrated in Laterally Confined DNA Monolayers 112
null 111
Evaluation of the contribution of the elongational factor 1 A isoforms in hepatocellular carcinoma celss growth 110
The Role of the eEF1A Family in Human Cancers 109
SiRNAs targeted against cyclin E1, cyclin E2 and E2F1 down regulate the growth of Hepatocellular Carcinoma showing their potential use in the prevention of this type of tumor 109
A siRNA targeted against SRF reduce hepatocellular carcinoma cell proliferation, showing its potential use in the growth inhibition of this type of tumor 109
Protein phosphorylation and neutrophil activation 108
“Alpha-anomeric configuration of GT oligodeoxynucleotide leads to loss of specific aptameric and cytotoxic properties retained by the Beta-anomeric analog” 107
“The expression levels of the translational factors eEF1A1/2 correlate with the cell growth but not apoptosis in hepatocellular carcinoma cell lines with different differentiation grade” 106
PDPG Polymer as a targeted delivery system for siRNAs to hepatocellular carcinoma cells 105
Effects of eEF1A1 targeting by aptamer/siRNA in chronic lymphocytic leukaemia cells 104
Triple-helix forming oligodeoxyribonucleotide, inhibiting mdr1 transcription may reduce mdr1 gene amplification level in multidrug-resistant leukaemic cell line 103
Repeated Implantations of human amniotic epithelial cells as a curative therapy of Niemann-Pick disease 103
The targeting of the elongation factor 1A by a DNA aptamer impairs the viability of hepatocarcinoma cells 102
Medicine, Biology and mathematics 101
Role of E2F1-cycline1-cycline2 circuit in hepatocellular carcinoma cell proliferation and therapeutic potential of its down-regulation by siRNAs 100
null 97
Potential Application Of Proteasome Inhibitor Bortezomib For Treatment Of Hepatocellular Carcinoma 90
“Impianto di cellule epiteliali amniotiche umane crioconservate in un soggetto affetto da malattia di Niemann-Pick tipo B.” 89
Evaluation of bortezomib impact on cell-cycle related genes in the hepatocellular carcinoma cell lines hepg2 and jhh6 by means of microarray analysis 88
Evaluation of circulating cell-free DNA and its integrity as a potential predictive biomarker of breast cancer onset: A pilot study 86
Potential Application Of Proteasome Inhibitor Bortezomib For the Treatment Of Hepatocellular Carcinoma 85
Identification of nuclear elongation factor 1 alpha as single-stranded DNA-binding protein specifically recognising GT oligodeoxynucleotides that exert a selective human cancer cell growth inhibition 84
“The anti-gene DNA strategy by triple helix directed oligodeoxyribonucleotides to modulate human mdr1 gene expression.” 83
Small, antibacterial and large, inactive peptides of neutrophil granules share immunoreactivity to a monoclonal antibody. 81
Effect of oligomer length and base substitutions on the cytotoxic activity and specific nuclear protein recognition of GTn oligonucleotides in the human leukemic CCRF-CEM cell line.” 81
Attivazione dell'espressione di elongation factor 1A2 nei tumori prostatici 79
Aptamers as targeting delivery devices or anti-cancer drugs for fighting tumors 76
“Effect of phosphorotioate modifications on the GTn oligodeoxynucleotide ability to recognise the single stranded DNA binding proteins specifically related to the human cancer cellular growth inhibition” 75
Ethoxylated polyethylenimine successfully enhances the cytotoxic activity of GT oligomers targeted to specific nuclear proteins in human T-Lymphoblastic cancer cells. 75
The more basic isoform of eEF1A relates to tumour cell phenotype and is modulated by hyper-proliferative/differentiating stimuli in normal lymphocytes and CCRF-CEM T-lymphoblasts 75
“Increase of therapeutic index of doxorubicin and vinblastine by aptameric oligonucleotide in human T-lymphoblastic drug-sensitive and multidrug-resistant cells.” 74
EEF1A1 (eukaryotic translation elongation factor 1 alpha 1). Atlas Genet Cytogenet Oncol Haematol. May 2009 . 74
Xenograft zebrafish models for the development of novel anti-hepatocellular carcinoma molecules 74
High eEF1A1 Protein Levels Mark Aggressive Prostate Cancers and the In Vitro Targeting of eEF1A1 Reveals the eEF1A1–Actin Complex as a New Potential Target for Therapy 74
Triple-stranded DNA: formation, stability and application in biology.” 73
null 73
dGT sequences specifically and selectively inhibiting growth of human cancer cell lines, recognise single-stranded DNA-binding proteins 73
In vivo specific loss of DNA amplification by intermolecular triple-helix forming oligodeoxyribonucleotides.” 73
Circulating cell-free nucleic acids as prognostic and therapy predictive tools for metastatic castrate-resistant prostate cancer 70
“Correlation between cytotoxic effect and binding to nuclear proteins of oligomeric d(GT)n sequences in human cancer CCRF-CEM cell line.” 69
GT75 oligonucleotide as therapeutically new antitumoral agent and new aptamer for diagnostic u 67
Impact of psychosocial, behavioral and lifestyle factors on subjective cognitive complaints and perceived quality of life in a large cohort of Italian breast cancer patients 66
“Alpha-anomeric configuration of GT-oligodeoxynucleotide leads to loss of the specific aptameric and cytotoxic properties retained by the beta-anomeric analogue.” 66
“Effect of phosphorothioate modifications on the ability of GTn oligodeoxynucleotides to specifically recognize single-stranded DNA-binding proteins and to affect human cancer cellular growth.” 65
siRNA, Ribozyme and Aptamer Oligonucleotides as Molecular Tools for the Control of Cell Proliferation in the Perspective of Supporting Therapies 64
Scalp cooling system to prevent alopecia: Effectiveness, psychological effects and feasibility 63
"Reduction of mdr1 gene amplification in human multidrug resistant LoVo dX cellline is promoted by triple-helix forming oligonucleotides" 61
“Restoring uptake and retention of daunorubicin and idarubicin in P170-related multidrug-resistance cells by low concentration D-verapamil, cyclosporin-A and SDZ PSC 833. ” 60
“Secretion of lysosomal hydrolases by cultured human amnion epithelial cells”. 59
Targeted delivery of siRNAs against hepatocellular carcinoma-related genes by a galactosylated polyaspartamide copolymer 58
“.Identification of different isoforms of eEF1A in the nuclear fraction of human T-lymphoblastic cancer cell lines specifically binding ot aptameric GT oligonucleotides.” 55
An Overview of siRNA Delivery Strategies for Urological Cancers 55
Totale 34.154
Categoria #
all - tutte 59.123
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 59.123


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20205.195 0 0 580 795 579 739 676 628 365 269 326 238
2020/20213.585 357 286 302 409 310 297 223 269 299 357 196 280
2021/20222.945 183 184 174 301 164 191 150 220 324 270 251 533
2022/20235.929 444 499 467 548 448 644 349 567 558 338 541 526
2023/20244.705 506 445 391 367 411 298 504 541 111 404 391 336
2024/20251.105 324 343 438 0 0 0 0 0 0 0 0 0
Totale 35.115