ArTS Archivio della ricerca di Trieste

SPALLUTO, GIAMPIERO
 Distribuzione geografica
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Continente #
NA - Nord America 15.238
EU - Europa 6.871
AS - Asia 6.410
SA - Sud America 757
AF - Africa 192
OC - Oceania 22
Continente sconosciuto - Info sul continente non disponibili 19
Totale 29.509
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Nazione #
US - Stati Uniti d'America 15.004
SG - Singapore 2.278
CN - Cina 1.538
IT - Italia 1.371
SE - Svezia 1.260
UA - Ucraina 708
BR - Brasile 599
PL - Polonia 580
HK - Hong Kong 570
VN - Vietnam 529
FR - Francia 485
DE - Germania 456
KR - Corea 432
GB - Regno Unito 399
NL - Olanda 379
FI - Finlandia 344
TR - Turchia 313
RU - Federazione Russa 271
IN - India 197
IE - Irlanda 167
BD - Bangladesh 150
BG - Bulgaria 140
CA - Canada 115
JP - Giappone 69
CH - Svizzera 68
BE - Belgio 53
AR - Argentina 50
IQ - Iraq 50
MA - Marocco 44
MX - Messico 44
ES - Italia 41
AT - Austria 39
ID - Indonesia 38
PK - Pakistan 36
CZ - Repubblica Ceca 34
ZA - Sudafrica 27
EC - Ecuador 25
EG - Egitto 25
MY - Malesia 25
SA - Arabia Saudita 24
CI - Costa d'Avorio 23
UZ - Uzbekistan 23
VE - Venezuela 22
CO - Colombia 20
IL - Israele 18
AU - Australia 17
EU - Europa 17
LT - Lituania 16
JM - Giamaica 15
CL - Cile 14
AZ - Azerbaigian 13
KE - Kenya 13
PH - Filippine 13
PE - Perù 12
AE - Emirati Arabi Uniti 11
JO - Giordania 11
SN - Senegal 11
TT - Trinidad e Tobago 11
DZ - Algeria 10
BZ - Belize 9
IR - Iran 9
TW - Taiwan 9
HN - Honduras 8
TH - Thailandia 8
TN - Tunisia 8
BY - Bielorussia 7
NG - Nigeria 7
PY - Paraguay 7
TG - Togo 7
OM - Oman 6
PT - Portogallo 6
RO - Romania 6
CR - Costa Rica 5
HU - Ungheria 5
KZ - Kazakistan 5
NP - Nepal 5
NZ - Nuova Zelanda 5
RS - Serbia 5
SY - Repubblica araba siriana 5
UY - Uruguay 5
AL - Albania 4
BB - Barbados 4
DK - Danimarca 4
ET - Etiopia 4
GT - Guatemala 4
KG - Kirghizistan 4
NO - Norvegia 4
PA - Panama 4
PR - Porto Rico 4
PS - Palestinian Territory 4
BN - Brunei Darussalam 3
BO - Bolivia 3
EE - Estonia 3
GE - Georgia 3
GR - Grecia 3
LV - Lettonia 3
SK - Slovacchia (Repubblica Slovacca) 3
SL - Sierra Leone 3
AM - Armenia 2
BA - Bosnia-Erzegovina 2
Totale 29.472
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Città #
Dallas 2.493
Singapore 1.373
Woodbridge 1.136
Fairfield 1.132
Ashburn 1.069
Houston 1.009
Ann Arbor 980
San Jose 737
Chandler 665
Jacksonville 635
Hefei 595
Wilmington 571
Hong Kong 545
Seattle 471
Warsaw 434
Seoul 419
Cambridge 396
Trieste 336
Beijing 329
Izmir 273
Princeton 257
Boardman 253
Amsterdam 232
Chicago 175
Columbus 175
The Dalles 169
Los Angeles 154
Dublin 153
Milan 150
Buffalo 145
Ho Chi Minh City 142
Lauterbourg 139
Sofia 139
Munich 135
Zgierz 131
Hanoi 124
Moscow 110
Santa Clara 105
London 102
New York 91
Frankfurt am Main 82
Helsinki 81
São Paulo 74
San Diego 70
Menlo Park 58
Mestre 58
Council Bluffs 57
Verona 56
Bern 50
North Bergen 50
Rome 48
Shanghai 46
Bremen 42
Brussels 42
Düsseldorf 42
Tokyo 42
Turku 41
West Jordan 41
Guangzhou 40
Toronto 38
Dearborn 36
Da Nang 32
Phoenix 32
Casablanca 28
Falls Church 27
Sacile 27
Vienna 27
Haiphong 26
Brooklyn 25
Des Moines 25
Chennai 24
Abidjan 23
Montreal 22
Orem 22
Redwood City 22
Brno 21
Dhaka 20
Nuremberg 20
Mumbai 19
Tashkent 18
Manchester 17
Rio de Janeiro 17
New Delhi 16
Norwalk 16
Pittsburgh 16
San Francisco 16
Baghdad 14
Bologna 14
Miano 14
Philadelphia 14
Zurich 14
Cairo 13
Fremont 13
Istanbul 13
Jakarta 13
Jinan 13
Nanjing 13
Padova 13
Udine 13
Atlanta 12
Totale 20.517
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Nome #
1,2,4-Triazolo[1,5-a]-1,3,5-triazine nucleus: a possible template for adenosine receptor subtypes. 857
[1,2,4]Triazolo[1,5-c]pyrimidines as adenosine receptor antagonists: Modifications at the 8 position to reach selectivity towards A3 adenosine receptor subtype 762
[1,2,4]Triazolo[1,5-a][1,3,5]Triazine Derivatives as Antagonists for the Adenosine Receptors: a Preliminary Study on Affinity at the A3 Subtype 717
1,2,4]Triazolo[1,5-c]pyrimidines as New Potent Human A3 Adenosine Receptor Antagonists. 681
[1,2,4]triazolo[1,5-c]pyrimidines as A(3) adenosine receptor antagonists 662
[1,2,4]Triazolo[1,5-c]pyrimidine Nucleus as Adenosine Receptor Antagonists: Shift in Selectivity from A2A to A3 Adenosine Receptors. 637
[1,2,4]Triazolo[1,5-c]pyrimidines as Tools to Investigate A3 Adenosine Receptors in Cancer Cell Lines 618
Discovery of indolylpiperazinylpyrimidines with dual-target profiles at adenosine A2A and dopamine D2 receptors for Parkinson's disease treatment 444
The Influence of the 1-(3-Trifluoromethyl-Benzyl)-1H-Pyrazole-4-yl Moiety on the Adenosine Receptors Affinity Profile of Pyrazolo[4,3-e][1,2,4]Triazolo[1,5-c]Pyrimidine Derivatives 441
A Triazolotriazine-Based Dual GSK-3β/CK-1δ Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition 397
Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines and Structurally Simplified Analogs. Chemistry and SAR Profile as Adenosine Receptor Antagonists 357
5,7-Disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazines as pharmacological tools to explore the antagonist selectivity profiles toward adenosine receptors 295
Scaffold decoration at positions 5 and 8 of 1,2,4-triazolo[1,5- c ]pyrimidines to explore the antagonist profiling on adenosine receptors: A preliminary structure-activity relationship study 289
ANTI-HIV PROPERTIES OF CATIONIC FULLERENE DERIVATIVES 280
A2Aadenosine receptor antagonists as therapeutic candidates: Are they still an interesting challenge? 280
Advances in Computational Techniques to Study GPCR-Ligand Recognition 272
. 6-Amino-2-mercapto-3H-pyrimidin-4-one derivatives as new candidates for the antagonism at the P2Y12 receptors 258
Glycogen Synthase Kinase 3β Involvement in Neuroinflammation and Neurodegenerative Diseases 251
Hemolytic Effects of Water-Soluble Fullerene Derivatives 250
null 245
Scaffold Repurposing of in-House Chemical Library toward the Identification of New Casein Kinase 1 δinhibitors 245
Mixed-reversible and covalent kinase inhibition as a possible new strategy to treat neuro-inflammatory/degenerative diseases 243
N8-Isopentyl and N8-Phenylethyl Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine Derivatives as Adenosine Receptor Antagonists 242
Chemical probes for the adenosine receptors 239
8-(2-Furyl)adenine derivatives as A2A adenosine receptor ligands 236
A new Multi-charged C60 Derivative: Synthesis and Biological Properties 233
Anti-inflammatory and anti-oxidant activity of a new class of phenyl-pyrazolone derivatives. 233
Developing novel classes of protein kinase CK1δ inhibitors by fusing [1,2,4]triazole with different bicyclic heteroaromatic systems 227
Synthesis and biological evaluation of a new class of acyl derivatives of 3-amino-1-phenyl-4,5-dihydro-1H-pyrazol-5-one as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors. 226
CC-1065 and Duocarmycins: Recent Developments 225
A facile and novel synthesis of N2-, C6-substituted pyrazolo[3,4- d ]pyrimidine-4 carboxylate derivatives as adenosine receptor antagonists 225
Carbon nanotube substrates boost neuronal electrical signaling 222
Targeting Protein Kinase CK1δ with Riluzole: Could It Be One of the Possible Missing Bricks to Interpret Its Effect in the Treatment of ALS from a Molecular Point of View? 219
null 217
Structural investigations on a novel class of 1,2,4-triazolo[1,5-c]pyrimidines as adenosine receptor antagonists. 216
null 214
A novel conjugated agent between dopamine and an A2A adenosine receptor antagonists as a potential anti-Parkinson multitarget approach. 211
Chapter 1: A3 adenosine receptor ligands in the treatment of inflammation and cancer 211
7-Substituted-5-amino-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonists: a study on the importance of modifications at the side chain on the activity and solubility 210
Design, synthesis and evaluation of new indolylpyrimidylpiperazines for gastrointestinal cancer therapy 210
Synthesis and anti-HIV properties of new water-soluble bis-functionalized [60]fullerene derivatives 202
"Dual Anta-Inhibitors" of the A(2A) Adenosine Receptor and Casein Kinase CK1delta: Synthesis, Biological Evaluation, and Molecular Modeling Studies 198
Synthesis of a Hybrid Fullerene-Trimethoxyindole-Oligonucleotide Conjugate 198
Design, Synthesis and Biological Properties of Fulleropyrrolidine Derivatives as Potential DNA Photo-Probes 197
G protein-coupled receptors as challenging druggable targets: insights from in silico studies 197
null 197
Synthesis, Biological properties and molecular modeling investigation of the first potent, selective and water soluble human A3 adenosine receptor antagonist 196
A facile and versatile route to the synthesis of fused 2-pyridones: Useful intermediates for policyclic systems 194
DNA-Photocleavage Agents 190
PYRAZOLO TRIAZOLO PYRIMIDINES AS ADENOSINE RECEPTOR ANTAGONISTS: EFFECT OF THE N-5 BOND TYPE ON THE AFFINITY AND SELECTIVITY AT THE FOUR ADENOSINE RECEPTOR SUBTYPES 186
Synthesis, biological activity and molecular modeling investigation of new pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives as human A3 adenosine receptor antagonists 185
Response surface analysis as alternative 3D-QSAR tool: human A3 adenosine receptor antagonists as a key study. 181
A Computational Workflow for the Identification of Novel Fragments Acting as Inhibitors of the Activity of Protein Kinase CK1δ 179
5-Alkylamino-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines. Influence of the Substituent on the Affinity at the Adenosine Receptor Subtypes 179
Adenosine Receptor Ligands, Probes, and Functional Conjugates: A 20-Year History of Pyrazolo[4,3-e][1,2,4]Triazolo[1,5-c]Pyrimidines (PTP) 179
Discovery of simplified N2-substituted pyrazolo[3,4-d]pyrimidine derivatives as novel adenosine receptor antagonists: Efficient synthetic approaches, biological evaluations and molecular docking studies 178
FLUORESCENT ANTAGONISTS OF THE A3 ADENOSINE RECEPTOR 178
The A3 adenosine receptor as multifaceted therapeutic Target: pharmacology, medicinal Chemistry, and In silico approaches 177
Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines to develop functionalized ligands to target adenosine receptors: fluorescent ligands as an example 176
Pyrazolo-triazolo-pyrimidine derivatives as adenosine receptor antagonists: A possible template for adenosine receptor subtypes? 175
Synthesis and Biological Studies of a New Series of 5-Heteroarylcarbamoylaminopyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists. Influence of the Heteroaryl Substituent on Binding Affinity and Molecular Modeling Investigations 175
Novel fluorescent hA3 adenosine receptor antagonists. 175
Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as adenosine receptor antagonists. Influence of the N5 substituent on the affinity at the human A(3) and A(2B) adenosine receptor subtypes: A molecular modeling investigation 172
Gaucher Disease: A Glance from a Medicinal Chemistry Perspective 170
Novel Versatile Fullerene Synthons 170
Progress in the pursuit of therapeutic adenosine receptor antagonists 170
[3H]MRE 3008-F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A3 adenosine receptors. 170
Synthesis and Molecular Modeling Studies of Fullerene-Trimethoxyindole-Oligonucleotide Conjugates as Possible Probes for Studying Photochemical Reactions in DNA Triple Helices 169
Conjugable A3 Adenosine Receptor Antagonists: Probing the 5 Position of the Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine Scaffold. 169
Biological Applications of Fullerene Derivatives: A Brief Overview 168
Ligand based-homology modeling as attractive tool to inspect GPCR structural plasticity 168
Synthesis and biological evaluation of new phenidone analogues as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors 167
Fluorescent ligands for the A3 adenosine receptor. 167
CVT 6975-like Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine Derivatives: an Attempt towards A2B Adenosine Receptor Affinity. 166
Rational Design, synthesis, and evaluation of a key analogues of CC-1065 and the duocarmycins. 165
The significance of 2-furyl ring substitution with a 2-(para-substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA3 adenosine receptor antagonists: new insights into structure affinity relathionship and receptor antagonist recognition. 164
Anticonvulsivanti 164
Conjugates between minor groove binders and Zn(II)-tach complexes: Synthesis, characterization, and interaction with plasmid DNA 163
The current status of pharmacotherapy for the treatment of Parkinson's disease: transition from single-target to multitarget therapy 163
Potent and selective A2A adenosine receptor antagonists: Recent Improvements 161
null 161
Synthesis and biological evaluation of a new series of 1,2,4-Triazolo(1,5-a)-1,3,5-triazines as human A2A adenosine receptor antagonists with improved water solubility 161
Adenine derivatives as inhibitors of the casein kinase CK1delta enzyme 160
New 2,6,9 tri-substituted adenines as adenosine receptor antagonists: a preliminary SAR profile. 157
Pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine Derivatives as Highly Potent and Selective Human A3 Adenosine Receptor Antagonists: Influence of the Chain at the N8 pyrazole Nitrogen. 156
Structural Investigations on a Novel Class of [1,2,4]Triazolo[1,5-c]pyrimidines as Adenosine Receptor Antagonists. 156
Revisiting a Receptor-Based Pharmacophore Hypothesis for Human A2A Adenosine Receptor Antagonists. 156
Fullerene derivatives: an actractive tool for biological application 155
null 154
Fullerene derivatives: an attractive tool for biological application 153
null 153
Pharmacological and biochemical characterization of A3 adenosine receptors in Jurkat T cells 152
Oligonucleotides and Oligonucleotide Conjugates: A New Approach for Cancer Treatment 151
New 9-methyl-8-(4-hydroxyphenyl)adenine derivatives as A1 adenosine receptor antagonists. 151
Conjugable A3 adenosine receptor antagonists for the development of functionalized ligands and their use in fluorescent probes 151
Revisiting a Receptor-Based Pharmacophore Hypothesis for Human A2A Adenosine Receptor Antagonists 146
Fluorescent ligands for adenosine receptors 145
Therapeutic potential of A2 and A3 adenosine receptor: a review of novel patented ligands. 144
Impact of protein-ligand solvation and desolvation on transition state thermodynamic properties of adenosine A2Aligand binding kinetics 144
Fluorosulfonyl- and Bis-(b-Chloroethyl)amino-Phenylamino Functionalized Pyrazolo[4,3-e]1,2,4-Triazolo[1,5-c]Pyrimidine Derivatives: Irreversible Antagonists at the Human A3 Adenosine Receptor and Molecular Modeling Studies 142
Totale 23.643
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Categoria #
all - tutte 78.956
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 78.956
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.767 121 148 76 390 23 101 66 59 176 216 88 303
2022/20232.252 203 268 162 303 224 438 6 202 288 31 91 36
2023/20241.486 113 109 82 127 113 94 210 337 5 72 107 117
2024/20253.522 115 122 387 298 269 305 187 186 438 414 270 531
2025/202610.453 838 1.299 2.487 677 523 642 1.082 274 912 1.127 337 255
2026/202796 96 0 0 0 0 0 0 0 0 0 0 0
Totale 30.017